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A CD8 T cell–intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo
Previous studies have indicated that blockade of signaling through the T-cell receptor (TCR)/calcineurin/nuclear factor of activated T cells (NFAT) pathway impairs transplantation tolerance induced with anti-CD154 antibody. By using an allogeneic bone marrow transplantation model, we examined the ro...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2826238/ https://ncbi.nlm.nih.gov/pubmed/20007805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-230680 |
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