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CTLA-4 on alloreactive CD4 T cells interacts with recipient CD80/86 to promote tolerance
Although the inhibitory receptor CTLA-4 (CD152) has been implicated in peripheral CD4 T-cell tolerance, its mechanism of action remains poorly defined. We analyzed mechanisms of CD4 cell tolerance in a model of tolerance induction involving establishment of mixed hematopoietic chimerism in recipient...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society of Hematology
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668856/ https://ncbi.nlm.nih.gov/pubmed/19179471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-01-133736 |
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