Trans-endocytosis of CD80 and CD86: a molecular basis for the cell extrinsic function of CTLA-4

CTLA-4 is an essential negative regulator of T cell immune responses whose mechanism of action is the subject of debate. CTLA-4 also shares two ligands (CD80 and CD86) with a stimulatory receptor, CD28. Here we show that CTLA-4 can capture its ligands from opposing cells by a process of trans-endocy...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Qureshi, Omar S., Zheng, Yong, Nakamura, Kyoko, Attridge, Kesley, Manzotti, Claire, Schmidt, Emily M., Baker, Jennifer, Jeffery, Louisa E., Kaur, Satdip, Briggs, Zoe, Hou, Tie Z., Futter, Clare E., Anderson, Graham, Walker, Lucy S.K., Sansom, David M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198051/
https://ncbi.nlm.nih.gov/pubmed/21474713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1202947
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia