Interaction of CTLA‐4 (CD152) with CD80 or CD86 inhibits human T‐cell activation

Occupancy of CTLA‐4 (cytotoxic T‐lymphocyte antigen‐4 or CD152) negatively regulates the activation of mouse T lymphocytes, as indicated by the fate of CTLA‐4‐deficient mice, by the impact of anti‐CTLA‐4 monoclonal antibodies (mAbs) on mouse T‐cell activation in vitro and by the impact of CTLA‐4 blo...

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Detalhes bibliográficos
Main Authors: Vandenborre, K, Van Gool, S W, Kasran, A, Ceuppens, J L, Boogaerts, M A, Vandenberghe, P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326945/
https://ncbi.nlm.nih.gov/pubmed/10583602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00888.x
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