Impact of Single-Nucleotide Polymorphisms of CTLA-4, CD80 and CD86 on the Effectiveness of Abatacept in Patients with Rheumatoid Arthritis

Abatacept (ABA) is used as a first-line treatment in patients diagnosed with moderate and severe rheumatoid arthritis (RA). The interindividual response to ABA therapy is very variable in these patients. The objective of our study was therefore to investigate the role of polymorphisms of the CTLA-4,...

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Detalhes bibliográficos
Publicado no:J Pers Med
Main Authors: Marquez Pete, Noelia, Maldonado Montoro, María del Mar, Pérez Ramírez, Cristina, Sánchez Martín, Almudena, Martínez de la Plata, Juan Enrique, Martínez Martínez, Fernando, Caliz Caliz, Rafael, Daddaoua, Abdelali, Ramírez Tortosa, María del Carmen, Jiménez Morales, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7711575/
https://ncbi.nlm.nih.gov/pubmed/33187286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm10040220
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