Influence of the FCGR2A rs1801274 and FCGR3A rs396991 Polymorphisms on Response to Abatacept in Patients with Rheumatoid Arthritis

Abatacept (ABA) is an immunosuppressant indicated for treatment of rheumatoid arthritis (RA). Effectiveness might be influenced by clinical RA variants and single-nucleotide polymorphisms (SNPs) in genes encoding protein FCGR2A (His131Arg) and FCGR3A (Phe158Val) involved in pharmacokinetics of ABA....

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發表在:J Pers Med
Main Authors: Márquez Pete, Noelia, Maldonado Montoro, María del Mar, Pérez Ramírez, Cristina, Martínez Martínez, Fernando, Martínez de la Plata, Juan Enrique, Daddaoua, Abdelali, Jiménez Morales, Alberto
格式: Artigo
語言:Inglês
出版: MDPI 2021
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233911/
https://ncbi.nlm.nih.gov/pubmed/34207385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm11060573
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