Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments

Por Veeranna, Yang, Dun-Sheng, Lee, Ju-Hyun, Vinod, K. Yaragudri, Stavrides, Philip, Amin, Niranjana D., Pant, Harish C., Nixon, Ralph A.
Publicado em 2009

Neuronal Apoptosis and Autophagy Cross Talk in Aging PS/APP Mice, a Model of Alzheimer’s Disease

Por Yang, Dun-Sheng, Kumar, Asok, Stavrides, Philip, Peterson, Jesse, Peterhoff, Corrine M., Pawlik, Monika, Levy, Efrat, Cataldo, Anne M., Nixon, Ralph A.
Publicado em 2008

Specific Calpain Inhibition by Calpastatin Prevents Tauopathy and Neurodegeneration and Restores Normal Lifespan in Tau P301L Mice

Por Rao, Mala V., McBrayer, Mary Kate, Campbell, Jabbar, Kumar, Asok, Hashim, Audrey, Sershen, Henry, Stavrides, Philip H., Ohno, Masuo, Hutton, Michael, Nixon, Ralph A.
Publicado em 2014

Defective macroautophagic turnover of brain lipids in the TgCRND8 Alzheimer mouse model: prevention by correcting lysosomal proteolytic deficits

Por Yang, Dun-Sheng, Stavrides, Philip, Saito, Mitsuo, Kumar, Asok, Rodriguez-Navarro, Jose A., Pawlik, Monika, Huo, Chunfeng, Walkley, Steven U., Saito, Mariko, Cuervo, Ana M., Nixon, Ralph A.
Publicado no Brain (2014)

Partial BACE1 Reduction in a Down Syndrome Mouse Model blocks Alzheimer-related Endosomal Anomalies and Cholinergic Neurodegeneration: Role of APP-CTF

Por Jiang, Ying, Rigoglioso, Andrew, Peterhoff, Corrinne M., Pawlik, Monika, Sato, Yutaka, Bleiwas, Cynthia, Stavrides, Philip, Smiley, John F., Ginsberg, Stephen D., Mathews, Paul M., Levy, Efrat, Nixon, Ralph A.
Publicado no Neurobiol Aging (2015)

Marked Calpastatin (CAST) Depletion in Alzheimer's Disease Accelerates Cytoskeleton Disruption and Neurodegeneration: Neuroprotection by CAST Overexpression

Por Rao, Mala V., Mohan, Panaiyur S., Peterhoff, Corrinne M., Yang, Dun-Sheng, Schmidt, Stephen D., Stavrides, Philip H., Campbell, Jabbar, Chen, Yuanxin, Jiang, Ying, Paskevich, Peter A., Cataldo, Anne M., Haroutunian, Vahram, Nixon, Ralph A.
Publicado em 2008

Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

Por Yang, Dun-Sheng, Stavrides, Philip, Mohan, Panaiyur S., Kaushik, Susmita, Kumar, Asok, Ohno, Masuo, Schmidt, Stephen D., Wesson, Daniel, Bandyopadhyay, Urmi, Jiang, Ying, Pawlik, Monika, Peterhoff, Corrinne M., Yang, Austin J., Wilson, Donald A., St George-Hyslop, Peter, Westaway, David, Mathews, Paul M., Levy, Efrat, Cuervo, Ana M., Nixon, Ralph A.
Publicado em 2011

Therapeutic effects of remediating autophagy failure in a mouse model of Alzheimer disease by enhancing lysosomal proteolysis

Por Yang, Dun-Sheng, Stavrides, Philip, Mohan, Panaiyur S, Kaushik, Susmita, Kumar, Asok, Ohno, Masuo, Schmidt, Stephen D, Wesson, Daniel W, Bandyopadhyay, Urmi, Jiang, Ying, Pawlik, Monika, Peterhoff, Corrinne M, Yang, Austin J, Wilson, Donald A, St George-Hyslop, Peter, Westaway, David, Mathews, Paul M, Levy, Efrat, Cuervo, Ana M, Nixon, Ralph A
Publicado em 2011