FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages

Por Fan, WuQiang, Morinaga, Hidetaka, Kim, Jane J, Bae, Eunju, Spann, Nathanael J, Heinz, Sven, Glass, Christopher K, Olefsky, Jerrold M
Publicado em 2010

Control of Pro-Inflammatory Gene Programs by Regulated Trimethylation and Demethylation of Histone H4K20

Por Stender, Joshua D., Pascual, Gabriel, Liu, Wen, Kaikkonen, Minna U., Do, Kevin, Spann, Nathanael J, Boutros, Michael, Perrimon, Norbert, Rosenfeld, Michael G., Glass, Christopher K.
Publicado em 2012

Txnip balances metabolic and growth signaling via PTEN disulfide reduction

Por Hui, Simon T. Y., Andres, Allen M., Miller, Amber K., Spann, Nathanael J., Potter, Douglas W., Post, Noah M., Chen, Amelia Z., Sachithanantham, Sowbarnika, Jung, Dae Young, Kim, Jason K., Davis, Roger A.
Publicado em 2008

Tissue damage drives co-localization of NF-κB, Smad3, and Nrf2 to direct Rev-erb sensitive wound repair in mouse macrophages

Por Eichenfield, Dawn Z, Troutman, Ty Dale, Link, Verena M, Lam, Michael T, Cho, Han, Gosselin, David, Spann, Nathanael J, Lesch, Hanna P, Tao, Jenhan, Muto, Jun, Gallo, Richard L, Evans, Ronald M, Glass, Christopher K
Publicado no eLife (2016)

SREBP1 contributes to resolution of pro-inflammatory TLR4 signaling by reprogramming fatty acid metabolism

Por Oishi, Yumiko, Spann, Nathanael J., Link, Verena M., Muse, Evan D., Strid, Tobias, Edillor, Chantle, Kolar, Matthew J., Matsuzaka, Takashi, Hayakawa, Sumio, Tao, Jenhan, Kaikkonen, Minna U., Carlin, Aaron F., Lam, Michael T., Manabe, Ichiro, Shimano, Hitoshi, Saghatelian, Alan, Glass, Christopher K.
Publicado no Cell Metab (2016)

NCoR REPRESSION OF LXRs RESTRICTS MACROPHAGE BIOSYNTHESIS OF INSULIN-SENSITIZING OMEGA 3 FATTY ACIDS

Por Li, Pingping, Spann, Nathanael J., Kaikkonen, Minna U., Lu, Min, Oh, Da Young, Fox, Jesse N., Bandyopadhyay, Gautam, Talukdar, Saswata, Xu, Jianfeng, Lagakos, William S., Patsouris, David, Armando, Aaron, Quehenberger, Oswald, Dennis, Edward A., Watkins, Steven M., Auwerx, Johan, Glass, Christopher K., Olefsky, Jerrold M.
Publicado em 2013

Cell-specific discrimination of desmosterol and desmosterol mimetics confers selective regulation of LXR and SREBP in macrophages

Por Muse, Evan D., Yu, Shan, Edillor, Chantle R., Tao, Jenhan, Spann, Nathanael J., Troutman, Ty D., Seidman, Jason S., Henke, Adam, Roland, Jason T., Ozeki, Katherine A., Thompson, Bonne M., McDonald, Jeffrey G., Bahadorani, John, Tsimikas, Sotirios, Grossman, Tamar R., Tremblay, Matthew S., Glass, Christopher K.
Publicado no Proc Natl Acad Sci U S A (2018)

Transcription factor ISL1 is essential for pacemaker development and function

Por Liang, Xingqun, Zhang, Qingquan, Cattaneo, Paola, Zhuang, Shaowei, Gong, Xiaohui, Spann, Nathanael J., Jiang, Cizhong, Cao, Xinkai, Zhao, Xiaodong, Zhang, Xiaoli, Bu, Lei, Wang, Gang, Chen, H.S. Vincent, Zhuang, Tao, Yan, Jie, Geng, Peng, Luo, Lina, Banerjee, Indroneal, Chen, Yihan, Glass, Christopher K., Zambon, Alexander C., Chen, Ju, Sun, Yunfu, Evans, Sylvia M.
Publicado no J Clin Invest (2015)

The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response

Por Blanc, Mathieu, Hsieh, Wei Yuan, Robertson, Kevin A., Kropp, Kai A., Forster, Thorsten, Shui, Guanghou, Lacaze, Paul, Watterson, Steven, Griffiths, Samantha J., Spann, Nathanael J., Meljon, Anna, Talbot, Simon, Krishnan, Kathiresan, Covey, Douglas F., Wenk, Markus R., Craigon, Marie, Ruzsics, Zsolts, Haas, Jürgen, Angulo, Ana, Griffiths, William J., Glass, Christopher K., Wang, Yuqin, Ghazal, Peter
Publicado em 2013

Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses

Por Spann, Nathanael J., Garmire, Lana X., McDonald, Jeffrey G., Myers, David S., Milne, Stephen B., Shibata, Norihito, Reichart, Donna, Fox, Jesse N., Shaked, Iftach, Heudobler, Daniel, Raetz, Christian R. H., Wang, Elaine W., Kelly, Samuel L., Sullards, M. Cameron, Murphy, Robert C., Merrill, Alfred H., Brown, H. Alex, Dennis, Edward A., Li, Andrew C., Ley, Klaus, Tsimikas, Sotirios, Fahy, Eoin, Subramaniam, Shankar, Quehenberger, Oswald, Russell, David W., Glass, Christopher K.
Publicado em 2012

25-Hydroxycholesterol Activates the Integrated Stress Response to Reprogram Transcription and Translation in Macrophages

Por Shibata, Norihito, Carlin, Aaron F., Spann, Nathanael J., Saijo, Kaoru, Morello, Christopher S., McDonald, Jeffrey G., Romanoski, Casey E., Maurya, Mano R., Kaikkonen, Minna U., Lam, Michael T., Crotti, Andrea, Reichart, Donna, Fox, Jesse N., Quehenberger, Oswald, Raetz, Christian R. H., Sullards, M. Cameron, Murphy, Robert C., Merrill, Alfred H., Brown, H. Alex, Dennis, Edward A., Fahy, Eoin, Subramaniam, Shankar, Cavener, Douglas R., Spector, Deborah H., Russell, David W., Glass, Christopher K.
Publicado em 2013

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions

Por Hoeksema, Marten A, Gijbels, Marion JJ, Van den Bossche, Jan, van der Velden, Saskia, Sijm, Ayestha, Neele, Annette E, Seijkens, Tom, Stöger, J Lauran, Meiler, Svenja, Boshuizen, Marieke CS, Dallinga-Thie, Geesje M, Levels, Johannes HM, Boon, Louis, Mullican, Shannon E, Spann, Nathanael J, Cleutjens, Jack P, Glass, Chris K, Lazar, Mitchell A, de Vries, Carlie JM, Biessen, Erik AL, Daemen, Mat JAP, Lutgens, Esther, de Winther, Menno PJ
Publicado em 2014

Biomarkers of NAFLD progression: a lipidomics approach to an epidemic(1)

Por Gorden, D. Lee, Myers, David S., Ivanova, Pavlina T., Fahy, Eoin, Maurya, Mano R., Gupta, Shakti, Min, Jun, Spann, Nathanael J., McDonald, Jeffrey G., Kelly, Samuel L., Duan, Jingjing, Sullards, M. Cameron, Leiker, Thomas J., Barkley, Robert M., Quehenberger, Oswald, Armando, Aaron M., Milne, Stephen B., Mathews, Thomas P., Armstrong, Michelle D., Li, Chijun, Melvin, Willie V., Clements, Ronald H., Washington, M. Kay, Mendonsa, Alisha M., Witztum, Joseph L., Guan, Ziqiang, Glass, Christopher K., Murphy, Robert C., Dennis, Edward A., Merrill, Alfred H., Russell, David W., Subramaniam, Shankar, Brown, H. Alex
Publicado no J Lipid Res (2015)