Cancer patients receiving immune checkpoint inhibitor therapy are at an increased risk for atherosclerotic cardiovascular disease

nork Lutgens, Esther, Seijkens, Tom T.P.
Argitaratua izan da J Immunother Cancer (2020)

E3 Ubiquitin Ligases as Immunotherapeutic Target in Atherosclerotic Cardiovascular Disease

nork Poels, Kikkie, Vos, Winnie G., Lutgens, Esther, Seijkens, Tom T. P.
Argitaratua izan da Front Cardiovasc Med (2020)

The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease

nork Bosmans, Laura A., Bosch, Lena, Kusters, Pascal J.H., Lutgens, Esther, Seijkens, Tom T.P.
Argitaratua izan da J Cardiovasc Transl Res (2020)

‘Nur'turing tumor T cell tolerance and exhaustion: novel function for Nuclear Receptor Nur77 in immunity

nork Lith, Sanne C., van Os, Bram W., Seijkens, Tom T.P., de Vries, Carlie J.M.
Argitaratua izan da Eur J Immunol (2020)

Immune checkpoint inhibitor treatment and atherosclerotic cardiovascular disease: an emerging clinical problem

nork Poels, Kikkie, Neppelenbroek, Suzanne I.M., Kersten, Marie José, Antoni, M. Louisa, Lutgens, Esther, Seijkens, Tom T.P.
Argitaratua izan da J Immunother Cancer (2021)

The CD40–CD40L Dyad in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

nork Aarts, Suzanne A. B. M., Seijkens, Tom T. P., van Dorst, Koos J. F., Dijkstra, Christine D., Kooij, Gijs, Lutgens, Esther
Argitaratua izan da Front Immunol (2017)

Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice

nork Poels, Kikkie, van Leent, Mandy M. T., Reiche, Myrthe E., Kusters, Pascal J. H., Huveneers, Stephan, de Winther, Menno P. J., Mulder, Willem J. M., Lutgens, Esther, Seijkens, Tom T. P.
Argitaratua izan da Cells (2020)

Caveolin-1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T-cell response

nork Engel, David, Beckers, Linda, Wijnands, Erwin, Seijkens, Tom, Lievens, Dirk, Drechsler, Maik, Gerdes, Norbert, Soehnlein, Oliver, Daemen, Mat J. A. P., Stan, Radu V., Biessen, Erik A. L., Lutgens, Esther
Argitaratua 2011

Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis

nork Aarts, Suzanne ABM, Seijkens, Tom TP, Kusters, Pascal JH, van Tiel, Claudia M, Reiche, Myrthe E, den Toom, Myrthe, Beckers, Linda, van Roomen, Cindy PAA, de Winther, Menno PJ, Kooij, Gijs, Lutgens, Esther
Argitaratua izan da J Pathol (2019)

Inhibition of PFKFB3 Hampers the Progression of Atherosclerosis and Promotes Plaque Stability

nork Poels, Kikkie, Schnitzler, Johan G., Waissi, Farahnaz, Levels, Johannes H. M., Stroes, Erik S. G., Daemen, Mat J. A. P., Lutgens, Esther, Pennekamp, Anne-Marije, De Kleijn, Dominique P. V., Seijkens, Tom T. P., Kroon, Jeffrey
Argitaratua izan da Front Cell Dev Biol (2020)

Plasmacytoid dendritic cells protect against atherosclerosis by tuning T cell proliferation and activity: Daissormont, Plasmacytoid dendritic cells and atherosclerosis

nork Daissormont, Isabelle T.M.N., Christ, Anette, Temmerman, Lieve, Millares, Stefan Sampedro, Seijkens, Tom, Rousch, Mat, Poggi, Marjorie, Boon, Louis, van der Loos, Chris, Daemen, Mat, Lutgens, Esther, Halvorsen, Bente, Aukrust, Pal, Janssen, Edith, Biessen, Erik A.L.
Argitaratua 2011

Hematopoietic G-protein-coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor-knockout mice

nork Otten, Jeroen J. T., de Jager, Saskia C. A., Kavelaars, Annemieke, Seijkens, Tom, Bot, Ilze, Wijnands, Erwin, Beckers, Linda, Westra, Marijke M., Bot, Martine, Busch, Matthias, Bermudez, Beatriz, van Berkel, Theo J. C., Heijnen, Cobi J., Biessen, Erik A. L.
Argitaratua 2013

Ablation of CD8α(+) dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice

nork Legein, Bart, Janssen, Edith M., Theelen, Thomas L., Gijbels, Marion J., Walraven, Joep, Klarquist, Jared S., Hennies, Cassandra M., Wouters, Kristiaan, Seijkens, Tom T.P., Wijnands, Erwin, Sluimer, Judith C., Lutgens, Esther, Zenke, Martin, Hildner, Kai, Biessen, Erik A.L., Temmerman, Lieve
Argitaratua izan da Sci Rep (2015)

Author Correction: Ablation of CD8α(+) dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice

nork Legein, Bart, Janssen, Edith M., Theelen, Thomas L., Gijbels, Marion J., Walraven, Joep, Klarquist, Jared S., Hennies, Cassandra M., Wouters, Kristiaan, Seijkens, Tom T. P., Wijnands, Erwin, Sluimer, Judith C., Lutgens, Esther, Zenke, Martin, Hildner, Kai, Biessen, Erik A. L., Temmerman, Lieve
Argitaratua izan da Sci Rep (2020)

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

nork Lutgens, Esther, Lievens, Dirk, Beckers, Linda, Wijnands, Erwin, Soehnlein, Oliver, Zernecke, Alma, Seijkens, Tom, Engel, David, Cleutjens, Jack, Keller, Anna M., Naik, Shalin H., Boon, Louis, Oufella, Hafid Ait, Mallat, Ziad, Ahonen, Cory L., Noelle, Randolph J., de Winther, Menno P., Daemen, Mat J., Biessen, Erik A., Weber, Christian
Argitaratua 2010

Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis

nork Lievens, Dirk, Zernecke, Alma, Seijkens, Tom, Soehnlein, Oliver, Beckers, Linda, Munnix, Imke C. A., Wijnands, Erwin, Goossens, Pieter, van Kruchten, Roger, Thevissen, Larissa, Boon, Louis, Flavell, Richard A., Noelle, Randolph J., Gerdes, Norbert, Biessen, Erik A., Daemen, Mat J. A. P., Heemskerk, Johan W. M., Weber, Christian, Lutgens, Esther
Argitaratua 2010

Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation

nork Aarts, Suzanne A. B. M., Seijkens, Tom T. P., Kusters, Pascal J. H., van der Pol, Susanne M. A., Zarzycka, Barbara, Heijnen, Priscilla D. A. M., Beckers, Linda, den Toom, Myrthe, Gijbels, Marion J. J., Boon, Louis, Weber, Christian, de Vries, Helga E., Nicolaes, Gerry A. F., Dijkstra, Christine D., Kooij, Gijs, Lutgens, Esther
Argitaratua izan da J Neuroinflammation (2017)

Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death

nork Seijkens, Tom T P, Poels, Kikkie, Meiler, Svenja, van Tiel, Claudia M, Kusters, Pascal J H, Reiche, Myrthe, Atzler, Dorothee, Winkels, Holger, Tjwa, Marc, Poelman, Hessel, Slütter, Bram, Kuiper, Johan, Gijbels, Marion, Kuivenhoven, Jan Albert, Matic, Ljubica Perisic, Paulsson-Berne, Gabrielle, Hedin, Ulf, Hansson, Göran K, Nicolaes, Gerry A F, Daemen, Mat J A P, Weber, Christian, Gerdes, Norbert, de Winther, Menno P J, Lutgens, Esther
Argitaratua izan da Eur Heart J (2019)

Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease

nork Lacy, Michael, Bürger, Christina, Shami, Annelie, Ahmadsei, Maiwand, Winkels, Holger, Nitz, Katrin, van Tiel, Claudia M., Seijkens, Tom T. P., Kusters, Pascal J. H., Karshovka, Ela, Prange, Koen H. M., Wu, Yuting, Brouns, Sanne L. N., Unterlugauer, Sigrid, Kuijpers, Marijke J. E., Reiche, Myrthe E., Steffens, Sabine, Edsfeldt, Andreas, Megens, Remco T. A., Heemskerk, Johan W. M., Goncalves, Isabel, Weber, Christian, Gerdes, Norbert, Atzler, Dorothee, Lutgens, Esther
Argitaratua izan da Nat Commun (2021)

Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions

nork Hoeksema, Marten A, Gijbels, Marion JJ, Van den Bossche, Jan, van der Velden, Saskia, Sijm, Ayestha, Neele, Annette E, Seijkens, Tom, Stöger, J Lauran, Meiler, Svenja, Boshuizen, Marieke CS, Dallinga-Thie, Geesje M, Levels, Johannes HM, Boon, Louis, Mullican, Shannon E, Spann, Nathanael J, Cleutjens, Jack P, Glass, Chris K, Lazar, Mitchell A, de Vries, Carlie JM, Biessen, Erik AL, Daemen, Mat JAP, Lutgens, Esther, de Winther, Menno PJ
Argitaratua 2014