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‘Nur'turing tumor T cell tolerance and exhaustion: novel function for Nuclear Receptor Nur77 in immunity

The nuclear receptor Nur77 is expressed in a multitude of tissues, regulating cell differentiation and homeostasis. Dysregulation of Nur77 signaling is associated with cancer, cardiovascular disease, and disorders of the CNS. The role of Nur77 in T cells has been studied for almost 30 years now. The...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Lith, Sanne C., van Os, Bram W., Seijkens, Tom T.P., de Vries, Carlie J.M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702156/
https://ncbi.nlm.nih.gov/pubmed/33063848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.202048869
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