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Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation
BACKGROUND: The influx of leukocytes into the central nervous system (CNS) is a key hallmark of the chronic neuro-inflammatory disease multiple sclerosis (MS). Strategies that aim to inhibit leukocyte migration across the blood-brain barrier (BBB) are therefore regarded as promising therapeutic appr...
Bewaard in:
Gepubliceerd in: | J Neuroinflammation |
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Hoofdauteurs: | , , , , , , , , , , , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
BioMed Central
2017
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5427621/ https://ncbi.nlm.nih.gov/pubmed/28494768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0875-9 |
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