25-Hydroxycholesterol Activates the Integrated Stress Response to Reprogram Transcription and Translation in Macrophages

25-Hydroxycholesterol (25OHC) is an enzymatically derived oxidation product of cholesterol that modulates lipid metabolism and immunity. 25OHC is synthesized in response to interferons and exerts broad antiviral activity by as yet poorly characterized mechanisms. To gain further insights into the ba...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shibata, Norihito, Carlin, Aaron F., Spann, Nathanael J., Saijo, Kaoru, Morello, Christopher S., McDonald, Jeffrey G., Romanoski, Casey E., Maurya, Mano R., Kaikkonen, Minna U., Lam, Michael T., Crotti, Andrea, Reichart, Donna, Fox, Jesse N., Quehenberger, Oswald, Raetz, Christian R. H., Sullards, M. Cameron, Murphy, Robert C., Merrill, Alfred H., Brown, H. Alex, Dennis, Edward A., Fahy, Eoin, Subramaniam, Shankar, Cavener, Douglas R., Spector, Deborah H., Russell, David W., Glass, Christopher K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Immunology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3861632/
https://ncbi.nlm.nih.gov/pubmed/24189069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.519637
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