Modeling of Eicosanoid Fluxes Reveals Functional Coupling between Cyclooxygenases and Terminal Synthases

Eicosanoids, including prostaglandins (PG) and leukotrienes, are lipid mediators derived from arachidonic acid. A quantitative and biochemical level understanding of eicosanoid metabolism would aid in understanding the mechanisms that govern inflammatory processes. Here, we present a combined experi...

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Hlavní autoři: Kihara, Yasuyuki, Gupta, Shakti, Maurya, Mano R., Armando, Aaron, Shah, Ishita, Quehenberger, Oswald, Glass, Christopher K., Dennis, Edward A., Subramaniam, Shankar
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2014
Témata:
Systems Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945033/
https://ncbi.nlm.nih.gov/pubmed/24559999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.01.015
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