Transcription factor ISL1 is essential for pacemaker development and function

The sinoatrial node (SAN) maintains a rhythmic heartbeat; therefore, a better understanding of factors that drive SAN development and function is crucial to generation of potential therapies, such as biological pacemakers, for sinus arrhythmias. Here, we determined that the LIM homeodomain transcrip...

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Pubblicato in:J Clin Invest
Autori principali: Liang, Xingqun, Zhang, Qingquan, Cattaneo, Paola, Zhuang, Shaowei, Gong, Xiaohui, Spann, Nathanael J., Jiang, Cizhong, Cao, Xinkai, Zhao, Xiaodong, Zhang, Xiaoli, Bu, Lei, Wang, Gang, Chen, H.S. Vincent, Zhuang, Tao, Yan, Jie, Geng, Peng, Luo, Lina, Banerjee, Indroneal, Chen, Yihan, Glass, Christopher K., Zambon, Alexander C., Chen, Ju, Sun, Yunfu, Evans, Sylvia M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563735/
https://ncbi.nlm.nih.gov/pubmed/26193633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68257
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