Transcription factor ISL1 is essential for pacemaker development and function

The sinoatrial node (SAN) maintains a rhythmic heartbeat; therefore, a better understanding of factors that drive SAN development and function is crucial to generation of potential therapies, such as biological pacemakers, for sinus arrhythmias. Here, we determined that the LIM homeodomain transcrip...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Liang, Xingqun, Zhang, Qingquan, Cattaneo, Paola, Zhuang, Shaowei, Gong, Xiaohui, Spann, Nathanael J., Jiang, Cizhong, Cao, Xinkai, Zhao, Xiaodong, Zhang, Xiaoli, Bu, Lei, Wang, Gang, Chen, H.S. Vincent, Zhuang, Tao, Yan, Jie, Geng, Peng, Luo, Lina, Banerjee, Indroneal, Chen, Yihan, Glass, Christopher K., Zambon, Alexander C., Chen, Ju, Sun, Yunfu, Evans, Sylvia M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4563735/
https://ncbi.nlm.nih.gov/pubmed/26193633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI68257
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