Collaborative ISL1/GATA3 interaction in controlling neuroblastoma oncogenic pathways overlapping with but distinct from MYCN

Background: Transcription factor ISL1 plays a critical role in sympathetic neurogenesis. Expression of ISL1 has been associated with neuroblastoma, a pediatric tumor derived from sympatho-adrenal progenitors, however the role of ISL1 in neuroblastoma remains unexplored. Method: Here, we knocked down...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Theranostics
Auteurs principaux: Zhang, Qitong, Zhang, Qingquan, Jiang, Xue, Ye, Youqiong, Liao, Huimin, Zhu, Fugui, Yan, Jie, Luo, Lina, Tian, Li, Jiang, Cizhong, Chen, Yihan, Liang, Xingqun, Sun, Yunfu
Format: Artigo
Langue:Inglês
Publié: Ivyspring International Publisher 2019
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401405/
https://ncbi.nlm.nih.gov/pubmed/30867811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.30199
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