NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma

Por Fionda, Cinzia, Soriani, Alessandra, Zingoni, Alessandra, Santoni, Angela, Cippitelli, Marco
Publicado no Biomed Res Int (2015)

CX3CR1/CX3CL1 axis negatively controls glioma cell invasion and is modulated by transforming growth factor-beta1

Por Sciumè, Giuseppe, Soriani, Alessandra, Piccoli, Mario, Frati, Luigi, Santoni, Angela, Bernardini, Giovanni
Publicado em 2010

Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma

Por Soriani, Alessandra, Fionda, Cinzia, Ricci, Biancamaria, Iannitto, Maria Luisa, Cippitelli, Marco, Santoni, Angela
Publicado em 2013

The DNA Damage Response: A Common Pathway in the Regulation of NKG2D and DNAM-1 Ligand Expression in Normal, Infected, and Cancer Cells

Por Cerboni, Cristina, Fionda, Cinzia, Soriani, Alessandra, Zingoni, Alessandra, Doria, Margherita, Cippitelli, Marco, Santoni, Angela
Publicado em 2014

Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells

Por Antonangeli, Fabrizio, Soriani, Alessandra, Ricci, Biancamaria, Ponzetta, Andrea, Benigni, Giorgia, Morrone, Stefania, Bernardini, Giovanni, Santoni, Angela
Publicado no Oncoimmunology (2016)

Axitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells

Por Morelli, Maria Beatrice, Amantini, Consuelo, Santoni, Matteo, Soriani, Alessandra, Nabissi, Massimo, Cardinali, Claudio, Santoni, Angela, Santoni, Giorgio
Publicado no Oncotarget (2015)

Integrin-mediated Ras–Extracellular Regulated Kinase (ERK) Signaling Regulates Interferon γ Production in Human Natural Killer Cells

Por Mainiero, Fabrizio, Gismondi, Angela, Soriani, Alessandra, Cippitelli, Marco, Palmieri, Gabriella, Jacobelli, Jordan, Piccoli, Mario, Frati, Luigi, Santoni, Angela
Publicado em 1998

Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation

Por Fionda, Cinzia, Abruzzese, Maria Pia, Zingoni, Alessandra, Soriani, Alessandra, Ricci, Biancamaria, Molfetta, Rosa, Paolini, Rossella, Santoni, Angela, Cippitelli, Marco
Publicado no BMC Cancer (2015)

Cannabinoids synergize with carfilzomib, reducing multiple myeloma cells viability and migration

Por Nabissi, Massimo, Morelli, Maria Beatrice, Offidani, Massimo, Amantini, Consuelo, Gentili, Silvia, Soriani, Alessandra, Cardinali, Claudio, Leoni, Pietro, Santoni, Giorgio
Publicado no Oncotarget (2016)

The Human Antibody Fragment DIATHIS1 Specific for CEACAM1 Enhances Natural Killer Cell Cytotoxicity Against Melanoma Cell Lines In Vitro

Por Dupuis, Maria L., Fiori, Valentina, Soriani, Alessandra, Ricci, Biancamaria, Dominici, Sabrina, Moricoli, Diego, Ascione, Alessandro, Santoni, Angela, Magnani, Mauro, Cianfriglia, Maurizio
Publicado no J Immunother (2015)

Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxic...

Por Amantini, Consuelo, Morelli, Maria Beatrice, Santoni, Matteo, Soriani, Alessandra, Cardinali, Claudio, Farfariello, Valerio, Eleuteri, Anna Maria, Bonfili, Laura, Mozzicafreddo, Matteo, Nabissi, Massimo, Cascinu, Stefano, Santoni, Giorgio
Publicado no Oncoscience (2015)

The IMiDs targets IKZF-1/3 and IRF4 as novel negative regulators of NK cell-activating ligands expression in multiple myeloma

Por Fionda, Cinzia, Abruzzese, Maria Pia, Zingoni, Alessandra, Cecere, Francesca, Vulpis, Elisabetta, Peruzzi, Giovanna, Soriani, Alessandra, Molfetta, Rosa, Paolini, Rossella, Ricciardi, Maria Rosaria, Petrucci, Maria Teresa, Santoni, Angela, Cippitelli, Marco
Publicado no Oncotarget (2015)

Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role...

Por Abruzzese, Maria Pia, Bilotta, Maria Teresa, Fionda, Cinzia, Zingoni, Alessandra, Soriani, Alessandra, Vulpis, Elisabetta, Borrelli, Cristiana, Zitti, Beatrice, Petrucci, Maria Teresa, Ricciardi, Maria Rosaria, Molfetta, Rosa, Paolini, Rossella, Santoni, Angela, Cippitelli, Marco
Publicado no J Hematol Oncol (2016)

Chemerin Regulates NK Cell Accumulation and Endothelial Cell Morphogenesis in the Decidua during Early Pregnancy

Por Carlino, Claudia, Trotta, Eleonora, Stabile, Helena, Morrone, Stefania, Bulla, Roberta, Soriani, Alessandra, Iannitto, Maria Luisa, Agostinis, Chiara, Mocci, Carlo, Minozzi, Massimo, Aragona, Cesare, Perniola, Giorgia, Tedesco, Francesco, Sozzani, Silvano, Santoni, Angela, Gismondi, Angela
Publicado em 2012

GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells

Por Barroeta Seijas, Amairelys Belen, Simonetti, Sonia, Vitale, Sara, Runci, Daniele, Quinci, Angela Caterina, Soriani, Alessandra, Criscuoli, Mattia, Filippi, Irene, Naldini, Antonella, Sacchetti, Federico Maria, Tarantino, Umberto, Oliva, Francesco, Piccirilli, Eleonora, Santoni, Angela, Di Rosa, Francesca
Publicado no Front Immunol (2017)

p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells

Por Soriani, Alessandra, Borrelli, Cristiana, Ricci, Biancamaria, Molfetta, Rosa, Zingoni, Alessandra, Fionda, Cinzia, Carnevale, Silvia, Abruzzese, Maria Pia, Petrucci, Maria Teresa, Ricciardi, Maria Rosaria, La Regina, Giuseppe, Di Cesare, Erica, Lavia, Patrizia, Silvestri, Romano, Paolini, Rossella, Cippitelli, Marco, Santoni, Angela
Publicado no Oncoimmunology (2016)

Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis

Por Vulpis, Elisabetta, Cecere, Francesca, Molfetta, Rosa, Soriani, Alessandra, Fionda, Cinzia, Peruzzi, Giovanna, Caracciolo, Giulio, Palchetti, Sara, Masuelli, Laura, Simonelli, Lucilla, D'Oro, Ugo, Abruzzese, Maria Pia, Petrucci, Maria Teresa, Ricciardi, Maria Rosaria, Paolini, Rossella, Cippitelli, Marco, Santoni, Angela, Zingoni, Alessandra
Publicado no Oncoimmunology (2017)

Design and Synthesis of 2-Heterocyclyl-3-arylthio-1H-indoles as Potent Tubulin Polymerization and Cell Growth Inhibitors with Improved Metabolic Stability

Por La Regina, Giuseppe, Bai, Ruoli, Rensen, Willeke, Coluccia, Antonio, Piscitelli, Francesco, Gatti, Valerio, Bolognesi, Alessio, Lavecchia, Antonio, Granata, Ilaria, Porta, Amalia, Maresca, Bruno, Soriani, Alessandra, Iannitto, Maria Luisa, Mariani, Marisa, Santoni, Angela, Brancale, Andrea, Ferlini, Cristiano, Dondio, Giulio, Varasi, Mario, Mercurio, Ciro, Hamel, Ernest, Lavia, Patrizia, Novellino, Ettore, Silvestri, Romano
Publicado em 2011

Toward Highly Potent Cancer Agents by Modulating the C-2 Group of the Arylthioindole Class of Tubulin Polymerization Inhibitors

Por La Regina, Giuseppe, Bai, Ruoli, Rensen, Whilelmina Maria, Di Cesare, Erica, Coluccia, Antonio, Piscitelli, Francesco, Famiglini, Valeria, Reggio, Alessia, Nalli, Marianna, Pelliccia, Sveva, Pozzo, Eleonora Da, Costa, Barbara, Granata, Ilaria, Porta, Amalia, Maresca, Bruno, Soriani, Alessandra, Iannitto, Maria Luisa, Santoni, Angela, Li, Junjie, Cona, Marlein Miranda, Chen, Feng, Ni, Yicheng, Brancale, Andrea, Dondio, Giulio, Vultaggio, Stefania, Varasi, Mario, Mercurio, Ciro, Martini, Claudia, Hamel, Ernest, Lavia, Patrizia, Novellino, Ettore, Silvestri, Romano
Publicado em 2012

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Depend...

Por La Regina, Giuseppe, Bai, Ruoli, Coluccia, Antonio, Famiglini, Valeria, Pelliccia, Sveva, Passacantilli, Sara, Mazzoccoli, Carmela, Ruggieri, Vitalba, Verrico, Annalisa, Miele, Andrea, Monti, Ludovica, Nalli, Marianna, Alfonsi, Romina, Di Marcotullio, Lucia, Gulino, Alberto, Ricci, Biancamaria, Soriani, Alessandra, Santoni, Angela, Caraglia, Michele, Porto, Stefania, Pozzo, Eleonora Da, Martini, Claudia, Brancale, Andrea, Marinelli, Luciana, Novellino, Ettore, Vultaggio, Stefania, Varasi, Mario, Mercurio, Ciro, Bigogno, Chiara, Dondio, Giulio, Hamel, Ernest, Lavia, Patrizia, Silvestri, Romano
Publicado no J Med Chem (2015)