Harnessing the Activation of RIG-I Like Receptors to Inhibit Glioblastoma Tumorigenesis

Por Bufalieri, Francesca, Basili, Irene, Di Marcotullio, Lucia, Infante, Paola
Publicado no Front Mol Neurosci (2021)

Targeting Hedgehog Signalling through the Ubiquitylation Process: The Multiple Roles of the HECT-E3 Ligase Itch

Por Infante, Paola, Lospinoso Severini, Ludovica, Bernardi, Flavia, Bufalieri, Francesca, Di Marcotullio, Lucia
Publicado no Cells (2019)

DUBs Activating the Hedgehog Signaling Pathway: A Promising Therapeutic Target in Cancer

Por Bufalieri, Francesca, Lospinoso Severini, Ludovica, Caimano, Miriam, Infante, Paola, Di Marcotullio, Lucia
Publicado no Cancers (Basel) (2020)

Drug Delivery Systems for Hedgehog Inhibitors in the Treatment of SHH-Medulloblastoma

Por Caimano, Miriam, Lospinoso Severini, Ludovica, Loricchio, Elena, Infante, Paola, Di Marcotullio, Lucia
Publicado no Front Chem (2021)

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

Por Rodier, Geneviève, Montagnoli, Alessia, Di Marcotullio, Lucia, Coulombe, Philippe, Draetta, Giulio F., Pagano, Michele, Meloche, Sylvain
Publicado em 2001

The interplay between microRNAs and the neurotrophin receptor tropomyosin-related kinase C controls proliferation of human neuroblastoma cells

Por Laneve, Pietro, Di Marcotullio, Lucia, Gioia, Ubaldo, Fiori, Micol E., Ferretti, Elisabetta, Gulino, Alberto, Bozzoni, Irene, Caffarelli, Elisa
Publicado em 2007

Discovery, characterization and potential roles of a novel NF-YAx splice variant in human neuroblastoma

Por Cappabianca, Lucia, Farina, Antonietta Rosella, Di Marcotullio, Lucia, Infante, Paola, De Simone, Daniele, Sebastiano, Michela, Mackay, Andrew Reay
Publicado no J Exp Clin Cancer Res (2019)

Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

Por Signoretti, Sabina, Di Marcotullio, Lucia, Richardson, Andrea, Ramaswamy, Sridhar, Isaac, Beth, Rue, Montserrat, Monti, Franco, Loda, Massimo, Pagano, Michele
Publicado em 2002

Oncogenic role of the ubiquitin ligase subunit Skp2 in human breast cancer

Por Signoretti, Sabina, Di Marcotullio, Lucia, Richardson, Andrea, Ramaswamy, Sridhar, Isaac, Beth, Rue, Montserrat, Monti, Franco, Loda, Massimo, Pagano, Michele
Publicado no J Clin Invest (2016)

Design and Synthesis of New Withaferin A Inspired Hedgehog Pathway Inhibitors

Por Bonandi, Elisa, Mori, Mattia, Infante, Paola, Basili, Irene, Di Marcotullio, Lucia, Calcaterra, Andrea, Catti, Federica, Botta, Bruno, Passarella, Daniele
Publicado no Chemistry (2021)

CNBP regulates wing development in Drosophila melanogaster by promoting IRES-dependent translation of dMyc

Por Antonucci, Laura, D’Amico, Davide, Di Magno, Laura, Coni, Sonia, Di Marcotullio, Lucia, Cardinali, Beatrice, Gulino, Alberto, Ciapponi, Laura, Canettieri, Gianluca
Publicado em 2014

Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells

Por Ferretti, Elisabetta, De Smaele, Enrico, Miele, Evelina, Laneve, Pietro, Po, Agnese, Pelloni, Marianna, Paganelli, Arianna, Di Marcotullio, Lucia, Caffarelli, Elisa, Screpanti, Isabella, Bozzoni, Irene, Gulino, Alberto
Publicado em 2008

Gli2 Acetylation at Lysine 757 Regulates Hedgehog-Dependent Transcriptional Output by Preventing Its Promoter Occupancy

Por Coni, Sonia, Antonucci, Laura, D'Amico, Davide, Di Magno, Laura, Infante, Paola, De Smaele, Enrico, Giannini, Giuseppe, Di Marcotullio, Lucia, Screpanti, Isabella, Gulino, Alberto, Canettieri, Gianluca
Publicado em 2013

Hedgehog controls neural stem cells through p53-independent regulation of Nanog

Por Po, Agnese, Ferretti, Elisabetta, Miele, Evelina, De Smaele, Enrico, Paganelli, Arianna, Canettieri, Gianluca, Coni, Sonia, Di Marcotullio, Lucia, Biffoni, Mauro, Massimi, Luca, Di Rocco, Concezio, Screpanti, Isabella, Gulino, Alberto
Publicado em 2010

Cullin3 - BTB Interface: A Novel Target for Stapled Peptides

Por de Paola, Ivan, Pirone, Luciano, Palmieri, Maddalena, Balasco, Nicole, Esposito, Luciana, Russo, Luigi, Mazzà, Daniela, Di Marcotullio, Lucia, Di Gaetano, Sonia, Malgieri, Gaetano, Vitagliano, Luigi, Pedone, Emilia, Zaccaro, Laura
Publicado no PLoS One (2015)

Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61

Por Calcaterra, Andrea, Iovine, Valentina, Botta, Bruno, Quaglio, Deborah, D’Acquarica, Ilaria, Ciogli, Alessia, Iazzetti, Antonia, Alfonsi, Romina, Lospinoso Severini, Ludovica, Infante, Paola, Di Marcotullio, Lucia, Mori, Mattia, Ghirga, Francesca
Publicado no J Enzyme Inhib Med Chem (2018)

Hedgehog Antagonist REN(KCTD11) Regulates Proliferation and Apoptosis of Developing Granule Cell Progenitors

Por Argenti, Beatrice, Gallo, Rita, Di Marcotullio, Lucia, Ferretti, Elisabetta, Napolitano, Maddalena, Canterini, Sonia, De Smaele, Enrico, Greco, Azzura, Fiorenza, Maria Teresa, Maroder, Marella, Screpanti, Isabella, Alesse, Edoardo, Gulino, Alberto
Publicado no J Neurosci (2005)

The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I

Por Bufalieri, Francesca, Caimano, Miriam, Lospinoso Severini, Ludovica, Basili, Irene, Paglia, Francesco, Sampirisi, Luigi, Loricchio, Elena, Petroni, Marialaura, Canettieri, Gianluca, Santoro, Antonio, D’Angelo, Luca, Infante, Paola, Di Marcotullio, Lucia
Publicado no Cancers (Basel) (2020)

Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth

Por Di Magno, Laura, Manzi, Daniela, D’Amico, Davide, Coni, Sonia, Macone, Alberto, Infante, Paola, Di Marcotullio, Lucia, De Smaele, Enrico, Ferretti, Elisabetta, Screpanti, Isabella, Agostinelli, Enzo, Gulino, Alberto, Canettieri, Gianluca
Publicado no Cell Cycle (2014)

Dual SMO/BRAF Inhibition by Flavonolignans from Silybum marianum †

Por Diukendjieva, Antonia, Zaharieva, Maya M., Mori, Mattia, Alov, Petko, Tsakovska, Ivanka, Pencheva, Tania, Najdenski, Hristo, Křen, Vladimír, Felici, Chiara, Bufalieri, Francesca, Di Marcotullio, Lucia, Botta, Bruno, Botta, Maurizio, Pajeva, Ilza
Publicado no Antioxidants (Basel) (2020)