The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I

Glioblastoma multiforme (GB) is the most malignant primary brain tumor in humans, with an overall survival of approximatively 15 months. The molecular heterogeneity of GB, as well as its rapid progression, invasiveness and the occurrence of drug-resistant cancer stem cells, limits the efficacy of th...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Bufalieri, Francesca, Caimano, Miriam, Lospinoso Severini, Ludovica, Basili, Irene, Paglia, Francesco, Sampirisi, Luigi, Loricchio, Elena, Petroni, Marialaura, Canettieri, Gianluca, Santoro, Antonio, D’Angelo, Luca, Infante, Paola, Di Marcotullio, Lucia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072305/
https://ncbi.nlm.nih.gov/pubmed/32019099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020321
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