Drug Delivery Systems for Hedgehog Inhibitors in the Treatment of SHH-Medulloblastoma

Medulloblastoma (MB) is a highly aggressive pediatric tumor of the cerebellum. Hyperactivation of the Hedgehog (HH) pathway is observed in about 30% of all MB diagnoses, thereby bringing out its pharmacological blockade as a promising therapeutic strategy for the clinical management of this malignan...

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Vydáno v:Front Chem
Hlavní autoři: Caimano, Miriam, Lospinoso Severini, Ludovica, Loricchio, Elena, Infante, Paola, Di Marcotullio, Lucia
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215655/
https://ncbi.nlm.nih.gov/pubmed/34164380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2021.688108
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