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A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth
Pharmacological Hedgehog (Hh) pathway inhibition has emerged as a valuable anticancer strategy. A number of small molecules able to block the pathway at the upstream receptor Smoothened (Smo) or the downstream effector glioma-associated oncogene 1 (Gli1) has been designed and developed. In a recent...
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| Pubblicato in: | Cancers (Basel) |
|---|---|
| Autori principali: | , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6826940/ https://ncbi.nlm.nih.gov/pubmed/31601026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11101518 |
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