The Transcription Factor EGR1 Localizes to the Nucleolus and Is Linked to Suppression of Ribosomal Precursor Synthesis

by Ponti, Donatella, Bellenchi, Gian Carlo, Puca, Rosa, Bastianelli, Daniela, Maroder, Marella, Ragona, Giuseppe, Roussel, Pascal, Thiry, Marc, Mercola, Dan, Calogero, Antonella
Published 2014

Hedgehog Antagonist REN(KCTD11) Regulates Proliferation and Apoptosis of Developing Granule Cell Progenitors

by Argenti, Beatrice, Gallo, Rita, Di Marcotullio, Lucia, Ferretti, Elisabetta, Napolitano, Maddalena, Canterini, Sonia, De Smaele, Enrico, Greco, Azzura, Fiorenza, Maria Teresa, Maroder, Marella, Screpanti, Isabella, Alesse, Edoardo, Gulino, Alberto
Published in J Neurosci (2005)

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

by Di Marcotullio, Lucia, Ferretti, Elisabetta, De Smaele, Enrico, Argenti, Beatrice, Mincione, Claudia, Zazzeroni, Francesca, Gallo, Rita, Masuelli, Laura, Napolitano, Maddalena, Maroder, Marella, Modesti, Andrea, Giangaspero, Felice, Screpanti, Isabella, Alesse, Edoardo, Gulino, Alberto
Published 2004

A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth

by Lospinoso Severini, Ludovica, Quaglio, Deborah, Basili, Irene, Ghirga, Francesca, Bufalieri, Francesca, Caimano, Miriam, Balducci, Silvia, Moretti, Marta, Romeo, Isabella, Loricchio, Elena, Maroder, Marella, Botta, Bruno, Mori, Mattia, Infante, Paola, Di Marcotullio, Lucia
Published in Cancers (Basel) (2019)

Ren : a novel, developmentally regulated gene that promotes neural cell differentiation

by Gallo, Rita, Zazzeroni, Francesca, Alesse, Edoardo, Mincione, Claudia, Borello, Ugo, Buanne, Pasquale, D'Eugenio, Roberta, Mackay, Andrew R., Argenti, Beatrice, Gradini, Roberto, Russo, Matteo A., Maroder, Marella, Cossu, Giulio, Frati, Luigi, Screpanti, Isabella, Gulino, Alberto
Published 2002

An Integrated Approach Identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated Genes in Developing Cerebellum and Medulloblastoma,

by De Smaele, Enrico, Fragomeli, Caterina, Ferretti, Elisabetta, Pelloni, Marianna, Po, Agnese, Canettieri, Gianluca, Coni, Sonia, Di Marcotullio, Lucia, Greco, Azzura, Moretti, Marta, Di Rocco, Concezio, Pazzaglia, Simona, Maroder, Marella, Screpanti, Isabella, Giannini, Giuseppe, Gulino, Alberto
Published 2008

Adult Human Biliary Tree Stem Cells Differentiate to β-Pancreatic Islet Cells by Treatment with a Recombinant Human Pdx1 Peptide

by Cardinale, Vincenzo, Puca, Rosa, Carpino, Guido, Scafetta, Gaia, Renzi, Anastasia, De Canio, Michele, Sicilia, Francesca, Nevi, Lorenzo, Casa, Domenico, Panetta, Rocco, Berloco, Pasquale Bartolomeo, Reid, Lola M., Federici, Giorgio, Gaudio, Eugenio, Maroder, Marella, Alvaro, Domenico
Published in PLoS One (2015)

NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest

by Diluvio, Giulia, Del Gaudio, Francesca, Giuli, Maria Valeria, Franciosa, Giulia, Giuliani, Eugenia, Palermo, Rocco, Besharat, Zein Mersini, Pignataro, Maria Gemma, Vacca, Alessandra, d’Amati, Giulia, Maroder, Marella, Talora, Claudio, Capalbo, Carlo, Bellavia, Diana, Checquolo, Saula
Published in Oncogenesis (2018)

Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma

by De Smaele, Enrico, Di Marcotullio, Lucia, Moretti, Marta, Pelloni, Marianna, Occhione, Maria Anna, Infante, Paola, Cucchi, Danilo, Greco, Azzura, Pietrosanti, Laura, Todorovic, Jelena, Coni, Sonia, Canettieri, Gianluca, Ferretti, Elisabetta, Bei, Roberto, Maroder, Marella, Screpanti, Isabella, Gulino, Alberto
Published 2011

Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation

by Coni, Sonia, Serrao, Silvia Maria, Yurtsever, Zuleyha Nihan, Di Magno, Laura, Bordone, Rosa, Bertani, Camilla, Licursi, Valerio, Ianniello, Zaira, Infante, Paola, Moretti, Marta, Petroni, Marialaura, Guerrieri, Francesca, Fatica, Alessandro, Macone, Alberto, De Smaele, Enrico, Di Marcotullio, Lucia, Giannini, Giuseppe, Maroder, Marella, Agostinelli, Enzo, Canettieri, Gianluca
Published in Cell Death Dis (2020)

KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2

by Spiombi, Eleonora, Angrisani, Annapaola, Fonte, Simone, De Feudis, Giuseppina, Fabretti, Francesca, Cucchi, Danilo, Izzo, Mariapaola, Infante, Paola, Miele, Evelina, Po, Agnese, Di Magno, Laura, Magliozzi, Roberto, Guardavaccaro, Daniele, Maroder, Marella, Canettieri, Gianluca, Giannini, Giuseppe, Ferretti, Elisabetta, Gulino, Alberto, Di Marcotullio, Lucia, Moretti, Marta, De Smaele, Enrico
Published in Oncogenesis (2019)

Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis

by Infante, Paola, Faedda, Roberta, Bernardi, Flavia, Bufalieri, Francesca, Lospinoso Severini, Ludovica, Alfonsi, Romina, Mazzà, Daniela, Siler, Mariangela, Coni, Sonia, Po, Agnese, Petroni, Marialaura, Ferretti, Elisabetta, Mori, Mattia, De Smaele, Enrico, Canettieri, Gianluca, Capalbo, Carlo, Maroder, Marella, Screpanti, Isabella, Kool, Marcel, Pfister, Stefan M., Guardavaccaro, Daniele, Gulino, Alberto, Di Marcotullio, Lucia
Published in Nat Commun (2018)

Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation

by Antonucci, Laura, Di Magno, Laura, D’Amico, Davide, Manni, Simona, Serrao, Silvia Maria, Di Pastena, Fiorella, Bordone, Rosa, Yurtsever, Zuleyha Nihan, Caimano, Miriam, Petroni, Marialaura, Giorgi, Alessandra, Schininà, Maria Eugenia, Yates, John r., Di Marcotullio, Lucia, De Smaele, Enrico, Checquolo, Saula, Capalbo, Carlo, Agostinelli, Enzo, Maroder, Marella, Coni, Sonia, Canettieri, Gianluca
Published in Int J Oncol (2018)