The Transcription Factor EGR1 Localizes to the Nucleolus and Is Linked to Suppression of Ribosomal Precursor Synthesis

por Ponti, Donatella, Bellenchi, Gian Carlo, Puca, Rosa, Bastianelli, Daniela, Maroder, Marella, Ragona, Giuseppe, Roussel, Pascal, Thiry, Marc, Mercola, Dan, Calogero, Antonella
Publicado 2014

Hedgehog Antagonist REN(KCTD11) Regulates Proliferation and Apoptosis of Developing Granule Cell Progenitors

por Argenti, Beatrice, Gallo, Rita, Di Marcotullio, Lucia, Ferretti, Elisabetta, Napolitano, Maddalena, Canterini, Sonia, De Smaele, Enrico, Greco, Azzura, Fiorenza, Maria Teresa, Maroder, Marella, Screpanti, Isabella, Alesse, Edoardo, Gulino, Alberto
Publicado en J Neurosci (2005)

REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma

por Di Marcotullio, Lucia, Ferretti, Elisabetta, De Smaele, Enrico, Argenti, Beatrice, Mincione, Claudia, Zazzeroni, Francesca, Gallo, Rita, Masuelli, Laura, Napolitano, Maddalena, Maroder, Marella, Modesti, Andrea, Giangaspero, Felice, Screpanti, Isabella, Alesse, Edoardo, Gulino, Alberto
Publicado 2004

A Smo/Gli Multitarget Hedgehog Pathway Inhibitor Impairs Tumor Growth

por Lospinoso Severini, Ludovica, Quaglio, Deborah, Basili, Irene, Ghirga, Francesca, Bufalieri, Francesca, Caimano, Miriam, Balducci, Silvia, Moretti, Marta, Romeo, Isabella, Loricchio, Elena, Maroder, Marella, Botta, Bruno, Mori, Mattia, Infante, Paola, Di Marcotullio, Lucia
Publicado en Cancers (Basel) (2019)

Ren : a novel, developmentally regulated gene that promotes neural cell differentiation

por Gallo, Rita, Zazzeroni, Francesca, Alesse, Edoardo, Mincione, Claudia, Borello, Ugo, Buanne, Pasquale, D'Eugenio, Roberta, Mackay, Andrew R., Argenti, Beatrice, Gradini, Roberto, Russo, Matteo A., Maroder, Marella, Cossu, Giulio, Frati, Luigi, Screpanti, Isabella, Gulino, Alberto
Publicado 2002

An Integrated Approach Identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated Genes in Developing Cerebellum and Medulloblastoma,

por De Smaele, Enrico, Fragomeli, Caterina, Ferretti, Elisabetta, Pelloni, Marianna, Po, Agnese, Canettieri, Gianluca, Coni, Sonia, Di Marcotullio, Lucia, Greco, Azzura, Moretti, Marta, Di Rocco, Concezio, Pazzaglia, Simona, Maroder, Marella, Screpanti, Isabella, Giannini, Giuseppe, Gulino, Alberto
Publicado 2008

Adult Human Biliary Tree Stem Cells Differentiate to β-Pancreatic Islet Cells by Treatment with a Recombinant Human Pdx1 Peptide

por Cardinale, Vincenzo, Puca, Rosa, Carpino, Guido, Scafetta, Gaia, Renzi, Anastasia, De Canio, Michele, Sicilia, Francesca, Nevi, Lorenzo, Casa, Domenico, Panetta, Rocco, Berloco, Pasquale Bartolomeo, Reid, Lola M., Federici, Giorgio, Gaudio, Eugenio, Maroder, Marella, Alvaro, Domenico
Publicado en PLoS One (2015)

NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest

por Diluvio, Giulia, Del Gaudio, Francesca, Giuli, Maria Valeria, Franciosa, Giulia, Giuliani, Eugenia, Palermo, Rocco, Besharat, Zein Mersini, Pignataro, Maria Gemma, Vacca, Alessandra, d’Amati, Giulia, Maroder, Marella, Talora, Claudio, Capalbo, Carlo, Bellavia, Diana, Checquolo, Saula
Publicado en Oncogenesis (2018)

Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma

por De Smaele, Enrico, Di Marcotullio, Lucia, Moretti, Marta, Pelloni, Marianna, Occhione, Maria Anna, Infante, Paola, Cucchi, Danilo, Greco, Azzura, Pietrosanti, Laura, Todorovic, Jelena, Coni, Sonia, Canettieri, Gianluca, Ferretti, Elisabetta, Bei, Roberto, Maroder, Marella, Screpanti, Isabella, Gulino, Alberto
Publicado 2011

Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation

por Coni, Sonia, Serrao, Silvia Maria, Yurtsever, Zuleyha Nihan, Di Magno, Laura, Bordone, Rosa, Bertani, Camilla, Licursi, Valerio, Ianniello, Zaira, Infante, Paola, Moretti, Marta, Petroni, Marialaura, Guerrieri, Francesca, Fatica, Alessandro, Macone, Alberto, De Smaele, Enrico, Di Marcotullio, Lucia, Giannini, Giuseppe, Maroder, Marella, Agostinelli, Enzo, Canettieri, Gianluca
Publicado en Cell Death Dis (2020)

KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2

por Spiombi, Eleonora, Angrisani, Annapaola, Fonte, Simone, De Feudis, Giuseppina, Fabretti, Francesca, Cucchi, Danilo, Izzo, Mariapaola, Infante, Paola, Miele, Evelina, Po, Agnese, Di Magno, Laura, Magliozzi, Roberto, Guardavaccaro, Daniele, Maroder, Marella, Canettieri, Gianluca, Giannini, Giuseppe, Ferretti, Elisabetta, Gulino, Alberto, Di Marcotullio, Lucia, Moretti, Marta, De Smaele, Enrico
Publicado en Oncogenesis (2019)

Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis

por Infante, Paola, Faedda, Roberta, Bernardi, Flavia, Bufalieri, Francesca, Lospinoso Severini, Ludovica, Alfonsi, Romina, Mazzà, Daniela, Siler, Mariangela, Coni, Sonia, Po, Agnese, Petroni, Marialaura, Ferretti, Elisabetta, Mori, Mattia, De Smaele, Enrico, Canettieri, Gianluca, Capalbo, Carlo, Maroder, Marella, Screpanti, Isabella, Kool, Marcel, Pfister, Stefan M., Guardavaccaro, Daniele, Gulino, Alberto, Di Marcotullio, Lucia
Publicado en Nat Commun (2018)

Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation

por Antonucci, Laura, Di Magno, Laura, D’Amico, Davide, Manni, Simona, Serrao, Silvia Maria, Di Pastena, Fiorella, Bordone, Rosa, Yurtsever, Zuleyha Nihan, Caimano, Miriam, Petroni, Marialaura, Giorgi, Alessandra, Schininà, Maria Eugenia, Yates, John r., Di Marcotullio, Lucia, De Smaele, Enrico, Checquolo, Saula, Capalbo, Carlo, Agostinelli, Enzo, Maroder, Marella, Coni, Sonia, Canettieri, Gianluca
Publicado en Int J Oncol (2018)