The RNA-Binding Ubiquitin Ligase MEX3A Affects Glioblastoma Tumorigenesis by Inducing Ubiquitylation and Degradation of RIG-I

Glioblastoma multiforme (GB) is the most malignant primary brain tumor in humans, with an overall survival of approximatively 15 months. The molecular heterogeneity of GB, as well as its rapid progression, invasiveness and the occurrence of drug-resistant cancer stem cells, limits the efficacy of th...

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Publicat a:Cancers (Basel)
Autors principals: Bufalieri, Francesca, Caimano, Miriam, Lospinoso Severini, Ludovica, Basili, Irene, Paglia, Francesco, Sampirisi, Luigi, Loricchio, Elena, Petroni, Marialaura, Canettieri, Gianluca, Santoro, Antonio, D’Angelo, Luca, Infante, Paola, Di Marcotullio, Lucia
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072305/
https://ncbi.nlm.nih.gov/pubmed/32019099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12020321
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