GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells

Stem cell factor (SCF), the ligand of c-kit, is a key cytokine for hematopoiesis. Hematopoietic precursors express c-kit, whereas differentiated cells of hematopoietic lineage are negative for this receptor, with the exception of NK cells, mast cells, and a few others. While it has long been recogni...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Barroeta Seijas, Amairelys Belen, Simonetti, Sonia, Vitale, Sara, Runci, Daniele, Quinci, Angela Caterina, Soriani, Alessandra, Criscuoli, Mattia, Filippi, Irene, Naldini, Antonella, Sacchetti, Federico Maria, Tarantino, Umberto, Oliva, Francesco, Piccirilli, Eleonora, Santoni, Angela, Di Rosa, Francesca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311071/
https://ncbi.nlm.nih.gov/pubmed/28261209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00147
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