GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells

Stem cell factor (SCF), the ligand of c-kit, is a key cytokine for hematopoiesis. Hematopoietic precursors express c-kit, whereas differentiated cells of hematopoietic lineage are negative for this receptor, with the exception of NK cells, mast cells, and a few others. While it has long been recogni...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Barroeta Seijas, Amairelys Belen, Simonetti, Sonia, Vitale, Sara, Runci, Daniele, Quinci, Angela Caterina, Soriani, Alessandra, Criscuoli, Mattia, Filippi, Irene, Naldini, Antonella, Sacchetti, Federico Maria, Tarantino, Umberto, Oliva, Francesco, Piccirilli, Eleonora, Santoni, Angela, Di Rosa, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311071/
https://ncbi.nlm.nih.gov/pubmed/28261209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00147
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