Engineering a single-agent cytokine-antibody fusion that selectively expands regulatory T cells for autoimmune disease therapy.

Por Spangler, Jamie B., Trotta, Eleonora, Tomala, Jakub, Peck, Ariana, Young, Tracy A., Savvides, Christina S., Silveria, Stephanie, Votavova, Petra, Salafsky, Joshua, Pande, Vijay S., Kovar, Marek, Bluestone, Jeffrey A., Garcia, K. Christopher
Publicado no J Immunol (2018)

Chemerin Regulates NK Cell Accumulation and Endothelial Cell Morphogenesis in the Decidua during Early Pregnancy

Por Carlino, Claudia, Trotta, Eleonora, Stabile, Helena, Morrone, Stefania, Bulla, Roberta, Soriani, Alessandra, Iannitto, Maria Luisa, Agostinis, Chiara, Mocci, Carlo, Minozzi, Massimo, Aragona, Cesare, Perniola, Giorgia, Tedesco, Francesco, Sozzani, Silvano, Santoni, Angela, Gismondi, Angela
Publicado em 2012

A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism

Por Trotta, Eleonora, Bessette, Paul H., Silveria, Stephanie L., Ely, Lauren K., Jude, Kevin M., Le, Duy T., Holst, Charles R., Coyle, Anthony, Potempa, Marc, Lanier, Lewis L., Garcia, K. Christopher, Crellin, Natasha K., Rondon, Isaac J., Bluestone, Jeffrey A.
Publicado no Nat Med (2018)

Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes

Por Sockolosky, Jonathan T., Trotta, Eleonora, Parisi, Giulia, Picton, Lora, Su, Leon L., Le, Alan C., Chhabra, Akanksha, Silveria, Stephanie L., George, Benson M., King, Indigo C., Tiffany, Matthew R., Jude, Kevin, Sibener, Leah V., Baker, David, Shizuru, Judith A., Ribas, Antoni, Bluestone, Jeffrey A., Garcia, K. Christopher
Publicado no Science (2018)