Recruitment and activation of PLCγ1 in T cells: a new insight into old domains

Por Braiman, Alex, Barda-Saad, Mira, Sommers, Connie L, Samelson, Lawrence E
Publicado em 2006

The LAT Story: A Tale of Cooperativity, Coordination, and Choreography

Por Balagopalan, Lakshmi, Coussens, Nathan P., Sherman, Eilon, Samelson, Lawrence E., Sommers, Connie L.
Publicado em 2010

Report on the 2018 Cancer, Autoimmunity, and Immunology Conference

Por Curran, Colleen S., Sommers, Connie L., Young, Howard A., Bourcier, Katarzyna, Mancini, Marie, Sharon, Elad
Publicado no J Immunol (2019)

Role of the Multiple T Cell Receptor (TCR)-ζ Chain Signaling Motifs in Selection of the T Cell Repertoire

Por Shores, Elizabeth W., Tran, Tom, Grinberg, Alexander, Sommers, Connie L., Shen, Howard, Love, Paul E.
Publicado em 1997

Knock-in Mutation of the Distal Four Tyrosines of Linker for Activation of T Cells Blocks Murine T Cell Development

Por Sommers, Connie L., Menon, Rashmi K., Grinberg, Alexander, Zhang, Weiguo, Samelson, Lawrence E., Love, Paul E.
Publicado em 2001

A Role for the Tec Family Tyrosine Kinase Txk in T Cell Activation and Thymocyte Selection

Por Sommers, Connie L., Rabin, Ronald L., Grinberg, Alexander, Tsay, Henry C., Farber, Joshua, Love, Paul E.
Publicado em 1999

LAT-Independent Erk Activation via Bam32-PLC-γ1-Pak1 Complexes: GTPase-Independent Pak1 Activation

Por Rouquette-Jazdanian, Alexandre K., Sommers, Connie L., Kortum, Robert L., Morrison, Deborah K., Samelson, Lawrence E.
Publicado em 2012

Absence of both Sos-1 and Sos-2 in peripheral CD4(+) T cells leads to PI3K pathway activation and defects in migration

Por Guittard, Geoffrey, Kortum, Robert L, Balagopalan, Lakshmi, Çuburu, Nicolas, Nguyen, Phan, Sommers, Connie L, Samelson, Lawrence E
Publicado no Eur J Immunol (2015)

Hierarchical nanostructure and synergy of multimolecular signalling complexes

Por Sherman, Eilon, Barr, Valarie A., Merrill, Robert K., Regan, Carole K., Sommers, Connie L., Samelson, Lawrence E.
Publicado no Nat Commun (2016)

c-Cbl-Mediated Regulation of LAT-Nucleated Signaling Complexes

Por Balagopalan, Lakshmi, Barr, Valarie A., Sommers, Connie L., Barda-Saad, Mira, Goyal, Amrita, Isakowitz, Matthew S., Samelson, Lawrence E.
Publicado em 2007

The Four Distal Tyrosines Are Required for LAT-dependent Signaling in FcɛRI-mediated Mast Cell Activation

Por Saitoh, Shin-ichiroh, Odom, Sandra, Gomez, Gregorio, Sommers, Connie L., Young, Howard A., Rivera, Juan, Samelson, Lawrence E.
Publicado em 2003

Function of Cd3ε-Mediated Signals in T Cell Development

Por Sommers, Connie L., Dejarnette, Jan B., Huang, Kun, Lee, Jan, El-Khoury, Dalal, Shores, Elizabeth W., Love, Paul E.
Publicado em 2000

Inactivation of c-Cbl Reverses Neonatal Lethality and T Cell Developmental Arrest of SLP-76–deficient Mice

Por Chiang, Y. Jeffrey, Sommers, Connie L., Jordan, Martha S., Gu, Hua, Samelson, Lawrence E., Koretzky, Gary A., Hodes, Richard J.
Publicado em 2004

Diacylglycerol Kinase ζ Limits the Generation of Natural Regulatory T Cells

Por Schmidt, Amanda M., Zou, Tao, Joshi, Rohan P., Leichner, Theresa M., Pimentel, Matthew A., Sommers, Connie L., Kambayashi, Taku
Publicado em 2013

Genetic evidence for the role of Erk activation in a lymphoproliferative disease of mice

Por Miyaji, Michihiko, Kortum, Robert L., Surana, Rishi, Li, Wenmei, Woolard, Kevin D., Simpson, R. Mark, Samelson, Lawrence E., Sommers, Connie L.
Publicado em 2009

miR-155 Controls Lymphoproliferation in LAT Mutant Mice by Restraining T-Cell Apoptosis via SHIP-1/mTOR and PAK1/FOXO3/BIM Pathways

Por Rouquette-Jazdanian, Alexandre K., Kortum, Robert L., Li, Wenmei, Merrill, Robert K., Nguyen, Phan H., Samelson, Lawrence E., Sommers, Connie L.
Publicado no PLoS One (2015)

Specific requirement for CD3ɛ in T cell development

Por DeJarnette, Jan B., Sommers, Connie L., Huang, Kun, Woodside, Kenneth J., Emmons, Rebecca, Katz, Kenneth, Shores, Elizabeth W., Love, Paul E.
Publicado em 1998

T Cell Development in Mice Lacking All T Cell Receptor ζ Family Members (ζ, η, and FcεRIγ)

Por Shores, Elizabeth W., Ono, Masao, Kawabe, Tsutomo, Sommers, Connie L., Tran, Tom, Lui, Kin, Udey, Mark C., Ravetch, Jeffrey, Love, Paul E.
Publicado em 1998

Deconstructing Ras Signaling in the Thymus

Por Kortum, Robert L., Sommers, Connie L., Pinski, John M., Alexander, Clayton P., Merrill, Robert K., Li, Wenmei, Love, Paul E., Samelson, Lawrence E.
Publicado em 2012

Targeted Sos1 deletion reveals its critical role in early T-cell development

Por Kortum, Robert L., Sommers, Connie L., Alexander, Clayton P., Pinski, John M., Li, Wenmei, Grinberg, Alex, Lee, Jan, Love, Paul E., Samelson, Lawrence E.
Publicado em 2011