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Diacylglycerol Kinase ζ Limits the Generation of Natural Regulatory T Cells
Natural regulatory T (nTreg) cells are important for maintaining tolerance to self and foreign antigens, and they are thought to develop from thymocytes that receive strong T cell receptor (TCR)-mediated signals in the thymus. TCR engagement leads to the activation of phospholipase C γ1, which gener...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4103616/ https://ncbi.nlm.nih.gov/pubmed/24280042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004411 |
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