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Diacylglycerol Kinase ζ Limits the Generation of Natural Regulatory T Cells

Natural regulatory T (nTreg) cells are important for maintaining tolerance to self and foreign antigens, and they are thought to develop from thymocytes that receive strong T cell receptor (TCR)-mediated signals in the thymus. TCR engagement leads to the activation of phospholipase C γ1, which gener...

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Detalhes bibliográficos
Main Authors: Schmidt, Amanda M., Zou, Tao, Joshi, Rohan P., Leichner, Theresa M., Pimentel, Matthew A., Sommers, Connie L., Kambayashi, Taku
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103616/
https://ncbi.nlm.nih.gov/pubmed/24280042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004411
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