Deconstructing Ras Signaling in the Thymus

Thymocytes must transit at least two distinct developmental checkpoints, governed by signals that emanate from either the pre-T cell receptor (pre-TCR) or the TCR to the small G protein Ras before emerging as functional T lymphocytes. Recent studies have shown a role for the Ras guanine exchange fac...

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Detalhes bibliográficos
Main Authors: Kortum, Robert L., Sommers, Connie L., Pinski, John M., Alexander, Clayton P., Merrill, Robert K., Li, Wenmei, Love, Paul E., Samelson, Lawrence E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416180/
https://ncbi.nlm.nih.gov/pubmed/22586275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00317-12
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