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Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells

Extracellular signal-regulated kinase (ERK) activation is important for both thymocyte development and T cell function. Classically, signal transduction from the T cell antigen receptor (TCR) to ERK is thought to be regulated by signaling from Ras guanine nucleotide exchange factors (GEFs), through...

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Detalhes bibliográficos
Main Authors: Kortum, Robert L., Rouquette-Jazdanian, Alexandre K., Samelson, Lawrence E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856398/
https://ncbi.nlm.nih.gov/pubmed/23506953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2013.02.004
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