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Recruitment and activation of PLCγ1 in T cells: a new insight into old domains
Engagement of the T-cell antigen receptor leads to recruitment of phospholipase Cγ1 (PLCγ1) to the LAT-nucleated signaling complex and to PLCγ1 activation in a tyrosine phosphorylation-dependent manner. The mechanism of PLCγ1 recruitment and the role of PLCγ1 Src homology (SH) domains in this proces...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383559/ https://ncbi.nlm.nih.gov/pubmed/16467851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600978 |
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