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The LAT Story: A Tale of Cooperativity, Coordination, and Choreography

The adapter molecule LAT is a nucleating site for multiprotein signaling complexes that are vital for the function and differentiation of T cells. Extensive investigation of LAT in multiple experimental systems has led to an integrated understanding of the formation, composition, regulation, dynamic...

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Autors principals: Balagopalan, Lakshmi, Coussens, Nathan P., Sherman, Eilon, Samelson, Lawrence E., Sommers, Connie L.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908767/
https://ncbi.nlm.nih.gov/pubmed/20610546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a005512
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