Glucuronidation and Covalent Protein Binding of Benoxaprofen and Flunoxaprofen in Sandwich-Cultured Rat and Human Hepatocytes

by Dong, Jennifer Q., Smith, Philip C.
Published 2009

Neuroendocrine Control of Sleep

by Smith, Philip C., Mong, Jessica A.
Published in Curr Top Behav Neurosci (2019)

Disposition of acetaminophen and indocyanine green in cystic fibrosis-knockout mice

by Kulkarni, Swarupa G., Pegram, Anita A., Smith, Philip C.
Published 2000

UGT concentrations in human rectal tissue after multidose, oral curcumin

by Asher, Gary N., Fallon, John K., Smith, Philip C.
Published in Pharmacol Res Perspect (2016)

Targeted Precise Quantification of 12 Human Recombinant Uridine-Diphosphate Glucuronosyl Transferase 1A and 2B Isoforms Using Nano-Ultra-High-Performance Liquid Chromatography/Tand...

by Fallon, John K., Neubert, Hendrik, Goosen, Theunis C., Smith, Philip C.
Published 2013

Differential detergent fractionation of membrane protein from small samples of hepatocytes and liver tissue for quantitative proteomic analysis of drug metabolizing enzymes and tra...

by Qasem, Rani J., Fallon, John K., Nautiyal, Manisha, Mosedale, Merrie, Smith, Philip C.
Published in J Pharm Sci (2020)

Evaluation of human primary intestinal monolayers for drug metabolizing capabilities

by Speer, Jennifer E., Wang, Yuli, Fallon, John K., Smith, Philip C., Allbritton, Nancy L.
Published in J Biol Eng (2019)

Influence of Clinical and Demographic Variables on Mycophenolic Acid Pharmacokinetics in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

by Joy, Melanie S, Hilliard, Tandrea, Hu, Yichun, Hogan, Susan L, Wang, Jinzhao, Falk, Ronald J, Smith, Philip C
Published 2009

Scaling factors for the in vitro–in vivo extrapolation (IV–IVE) of renal drug and xenobiotic glucuronidation clearance

by Knights, Kathleen M., Spencer, Shane M., Fallon, John K., Chau, Nuy, Smith, Philip C., Miners, John O.
Published in Br J Clin Pharmacol (2016)

Targeted quantitative proteomic analysis of drug metabolizing enzymes and transporters by nano LC-MS/MS in the sandwich cultured human hepatocyte model

by Khatri, Raju, Fallon, John K., Rementer, Rebecca J. B., Kulick, Natasha T., Lee, Craig R., Smith, Philip C.
Published in J Pharmacol Toxicol Methods (2019)

Expansion of Knowledge on OCT1 Variant Activity In Vitro and In Vivo Using Oct1/2(−/−) Mice

by Morse, Bridget L., Chen, Lisa Hong, Catlow, John T., Fallon, John K., Smith, Philip C., Hillgren, Kathleen M.
Published in Front Pharmacol (2021)

Hepatic Metabolism and Biliary Excretion of Silymarin Flavonolignans in Isolated Perfused Rat Livers: Role of Mrp2 (Abcc2)

by Miranda, Sonia R., Lee, Jin Kyung, Brouwer, Kim L.R., Wen, Zhiming, Smith, Philip C., Hawke, Roy L.
Published 2008

Pharmacokinetics of Mycophenolic Acid in Patients with Lupus Nephritis

by Joy, Melanie S., Hilliard, Tandrea, Hu, Yichun, Hogan, Susan L., Dooley, Mary Anne, Falk, Ronald J., Smith, Philip C.
Published 2009

Safety and Pharmacokinetics of Bevirimat (PA-457), a Novel Inhibitor of Human Immunodeficiency Virus Maturation, in Healthy Volunteers

by Martin, David E., Blum, Robert, Wilton, John, Doto, Judy, Galbraith, Hal, Burgess, Gina L., Smith, Philip C., Ballow, Charles
Published 2007

Quantification of Human Uridine-Diphosphate Glucuronosyl Transferase (UGT) 1A Isoforms in Liver, Intestine and Kidney using nanoLC-MS/MS

by Harbourt, David E, Fallon, John K, Ito, Shinya, Baba, Takashi, Ritter, Joseph K, Glish, Gary L, Smith, Philip C
Published 2011

Quantitative Profiling of Human Renal UDP-glucuronosyltransferases and Glucuronidation Activity: A Comparison of Normal and Tumoral Kidney Tissues

by Margaillan, Guillaume, Rouleau, Michèle, Fallon, John K., Caron, Patrick, Villeneuve, Lyne, Turcotte, Véronique, Smith, Philip C., Joy, Melanie S., Guillemette, Chantal
Published in Drug Metab Dispos (2015)

Characterization of Primary Mouse Hepatocyte Spheroids as a Model System to Support Investigations of Drug-Induced Liver Injury

by Nautiyal, Manisha, Qasem, Rani J., Fallon, John K., Wolf, Kristina K., Liu, Jingli, Dixon, Darlene, Smith, Philip C., Mosedale, Merrie
Published in Toxicol In Vitro (2020)

Carboxylesterase Activities and Protein Expression in Rabbit and Pig Ocular Tissues

by Hammid, Anam, Fallon, John K., Lassila, Toni, Salluce, Giulia, Smith, Philip C., Tolonen, Ari, Sauer, Achim, Urtti, Arto, Honkakoski, Paavo
Published in Mol Pharm (2021)

Potent Activity of the HIV-1 Maturation Inhibitor Bevirimat in SCID-hu Thy/Liv Mice

by Stoddart, Cheryl A., Joshi, Pheroze, Sloan, Barbara, Bare, Jennifer C., Smith, Philip C., Allaway, Graham P., Wild, Carl T., Martin, David E.
Published 2007

Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential

by Margaillan, Guillaume, Rouleau, Michèle, Klein, Kathrin, Fallon, John K., Caron, Patrick, Villeneuve, Lyne, Smith, Philip C., Zanger, Ulrich M., Guillemette, Chantal
Published in Drug Metab Dispos (2015)