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Evaluation of human primary intestinal monolayers for drug metabolizing capabilities
BACKGROUND: The intestinal epithelium is a major site of drug metabolism in the human body, possessing enterocytes that house brush border enzymes and phase I and II drug metabolizing enzymes (DMEs). The enterocytes are supported by a porous extracellular matrix (ECM) that enables proper cell adhesi...
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| Publicado no: | J Biol Eng |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6829970/ https://ncbi.nlm.nih.gov/pubmed/31709009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0212-1 |
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