Characterization of Primary Mouse Hepatocyte Spheroids as a Model System to Support Investigations of Drug-Induced Liver Injury

Primary mouse hepatocytes isolated from genetically defined and/or diverse lines and disease models are a valuable resource for studying the impact of genetic and environmental factors on drug response and disease. However, standard monolayer cultures result in a rapid decline in mouse hepatocyte vi...

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Bibliografiske detaljer
Udgivet i:Toxicol In Vitro
Main Authors: Nautiyal, Manisha, Qasem, Rani J., Fallon, John K., Wolf, Kristina K., Liu, Jingli, Dixon, Darlene, Smith, Philip C., Mosedale, Merrie
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7736539/
https://ncbi.nlm.nih.gov/pubmed/33022361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tiv.2020.105010
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