UGT concentrations in human rectal tissue after multidose, oral curcumin

Por Asher, Gary N., Fallon, John K., Smith, Philip C.
Publicado no Pharmacol Res Perspect (2016)

Targeted Precise Quantification of 12 Human Recombinant Uridine-Diphosphate Glucuronosyl Transferase 1A and 2B Isoforms Using Nano-Ultra-High-Performance Liquid Chromatography/Tand...

Por Fallon, John K., Neubert, Hendrik, Goosen, Theunis C., Smith, Philip C.
Publicado em 2013

Extreme low dose of 5-fluorouracil reverses MDR in cancer by sensitizing cancer associated fibroblasts and down-regulating P-gp

Por Ma, Yan, Wang, Yuhua, Xu, Zhenghong, Wang, Yongjun, Fallon, John K., Liu, Feng
Publicado no PLoS One (2017)

Differential detergent fractionation of membrane protein from small samples of hepatocytes and liver tissue for quantitative proteomic analysis of drug metabolizing enzymes and tra...

Por Qasem, Rani J., Fallon, John K., Nautiyal, Manisha, Mosedale, Merrie, Smith, Philip C.
Publicado no J Pharm Sci (2020)

Evaluation of human primary intestinal monolayers for drug metabolizing capabilities

Por Speer, Jennifer E., Wang, Yuli, Fallon, John K., Smith, Philip C., Allbritton, Nancy L.
Publicado no J Biol Eng (2019)

Role of Organic Solute Transporter Alpha/Beta in Hepatotoxic Bile Acid Transport and Drug Interactions

Por Beaudoin, James J, Bezençon, Jacqueline, Sjöstedt, Noora, Fallon, John K, Brouwer, Kim L R
Publicado no Toxicol Sci (2020)

Pharmacokinetics of Sequential Doses of Capreomycin Powder for Inhalation in Guinea Pigs

Por Garcia-Contreras, L., Muttil, Pavan, Fallon, John K., Kabadi, Mohan, Gerety, Robert, Hickey, Anthony J.
Publicado em 2012

New mouse xenograft model modulated by tumor-associated fibroblasts for human multi-drug resistance in cancer

Por MA, YAN, LIN, ZHIQIANG, FALLON, JOHN K., ZHAO, QIANG, LIU, DAN, WANG, YONGJUN, LIU, FENG
Publicado no Oncol Rep (2015)

Scaling factors for the in vitro–in vivo extrapolation (IV–IVE) of renal drug and xenobiotic glucuronidation clearance

Por Knights, Kathleen M., Spencer, Shane M., Fallon, John K., Chau, Nuy, Smith, Philip C., Miners, John O.
Publicado no Br J Clin Pharmacol (2016)

Targeted quantitative proteomic analysis of drug metabolizing enzymes and transporters by nano LC-MS/MS in the sandwich cultured human hepatocyte model

Por Khatri, Raju, Fallon, John K., Rementer, Rebecca J. B., Kulick, Natasha T., Lee, Craig R., Smith, Philip C.
Publicado no J Pharmacol Toxicol Methods (2019)

Expansion of Knowledge on OCT1 Variant Activity In Vitro and In Vivo Using Oct1/2(−/−) Mice

Por Morse, Bridget L., Chen, Lisa Hong, Catlow, John T., Fallon, John K., Smith, Philip C., Hillgren, Kathleen M.
Publicado no Front Pharmacol (2021)

The effect of 3,4-methylenedioxymethamphetamine (MDMA, ?ecstasy?) and its metabolites on neurohypophysial hormone release from the isolated rat hypothalamus

Por Forsling, Mary L, Fallon, John K, Shah, Darshna, Tilbrook, Gary S, Cowan, David A, Kicman, Andrew T, Hutt, Andrew J
Publicado em 2002

Quantification of Human Uridine-Diphosphate Glucuronosyl Transferase (UGT) 1A Isoforms in Liver, Intestine and Kidney using nanoLC-MS/MS

Por Harbourt, David E, Fallon, John K, Ito, Shinya, Baba, Takashi, Ritter, Joseph K, Glish, Gary L, Smith, Philip C
Publicado em 2011

Combinational Delivery of Hydrophobic and Hydrophilic Anticancer Drugs in Single Nanoemulsions To Treat MDR in Cancer

Por Ma, Yan, Liu, Dan, Wang, Dun, Wang, Yongjun, Fu, Qiang, Fallon, John K., Yang, Xinggang, He, Zhonggui, Liu, Feng
Publicado em 2014

Quantitative Profiling of Human Renal UDP-glucuronosyltransferases and Glucuronidation Activity: A Comparison of Normal and Tumoral Kidney Tissues

Por Margaillan, Guillaume, Rouleau, Michèle, Fallon, John K., Caron, Patrick, Villeneuve, Lyne, Turcotte, Véronique, Smith, Philip C., Joy, Melanie S., Guillemette, Chantal
Publicado no Drug Metab Dispos (2015)

Characterization of Primary Mouse Hepatocyte Spheroids as a Model System to Support Investigations of Drug-Induced Liver Injury

Por Nautiyal, Manisha, Qasem, Rani J., Fallon, John K., Wolf, Kristina K., Liu, Jingli, Dixon, Darlene, Smith, Philip C., Mosedale, Merrie
Publicado no Toxicol In Vitro (2020)

Multiplexed Targeted Quantitative Proteomics Predicts Hepatic Glucuronidation Potential

Por Margaillan, Guillaume, Rouleau, Michèle, Klein, Kathrin, Fallon, John K., Caron, Patrick, Villeneuve, Lyne, Smith, Philip C., Zanger, Ulrich M., Guillemette, Chantal
Publicado no Drug Metab Dispos (2015)

Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking

Por Speer, Jennifer E., Gunasekara, Dulan B., Wang, Yuli, Fallon, John K., Attayek, Peter J., Smith, Philip C., Sims, Christopher E., Allbritton, Nancy L.
Publicado no J Biol Eng (2019)

Endogenous Coproporphyrin I and III Are Altered in Multidrug Resistance-Associated Protein 2-Deficient (TR(−)) Rats

Por Bezençon, Jacqueline, Saran, Chitra, Hussner, Janine, Beaudoin, James J., Zhang, Yueping, Shen, Hong, Fallon, John K., Smith, Philip C., zu Schwabedissen, Henriette E. Meyer, Brouwer, Kim L.R.
Publicado no J Pharm Sci (2020)

A monolayer of primary colonic epithelium generated on a scaffold with a gradient of stiffness for drug transport studies

Por Gunasekara, Dulan B., Speer, Jennifer, Wang, Yuli, Nguyen, Daniel L., Reed, Mark I., Smiddy, Nicole M., Parker, Joel S., Fallon, John K., Smith, Philip C., Sims, Christopher E., Magness, Scott T., Allbritton, Nancy L.
Publicado no Anal Chem (2018)