You are lost without a map: Navigating the sea of protein structures

Yazar: Lamb, Audrey L., Kappock, T. Joseph, Silvaggi, Nicholas R.
Yayımlandı Biochim Biophys Acta (2014)

Binding Energy and Catalysis by D-Xylose Isomerase: Kinetic, Product and X-Ray Crystallographic Analysis of Enzyme-Catalyzed Isomerization of (R)-Glyceraldehyde(, )

Yazar: Toteva, Maria M., Silvaggi, Nicholas R., Allen, Karen N., Richard, John P.
Baskı/Yayın Bilgisi 2011

Molecular Basis for ADP-ribose Binding to the Mac1 Domain of SARS-CoV-2 Nsp3

Yazar: Frick, David N., Virdi, Rajdeep S., Vuksanovic, Nemanja, Dahal, Narayan, Silvaggi, Nicholas R.
Yayımlandı Biochemistry (2020)

Periplasmic Cytophaga hutchinsonii Endoglucanases Are Required for Use of Crystalline Cellulose as the Sole Source of Carbon and Energy

Yazar: Zhu, Yongtao, Han, Lanlan, Hefferon, Kathleen L., Silvaggi, Nicholas R., Wilson, David B., McBride, Mark J.
Yayımlandı Appl Environ Microbiol (2016)

Evaluation of adamantane hydroxamates as botulinum neurotoxin inhibitors: synthesis, crystallography, modeling, kinetic and cellular based studies

Yazar: Šilhár, Peter, Silvaggi, Nicholas R., Pellett, Sabine, Čapková, Kateřina, Johnson, Eric A., Allen, Karen N., Janda, Kim D.
Baskı/Yayın Bilgisi 2012

Structural characterization of three noncanonical NTF2-like superfamily proteins: implications for polyketide biosynthesis

Yazar: Vuksanovic, Nemanja, Zhu, Xuechen, Serrano, Dante A., Siitonen, Vilja, Metsä-Ketelä, Mikko, Melançon, Charles E., Silvaggi, Nicholas R.
Yayımlandı Acta Crystallogr F Struct Biol Commun (2020)

Discovery of Drug-like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3

Yazar: Virdi, Rajdeep S., Bavisotto, Robert V., Hopper, Nicholas C., Vuksanovic, Nemanja, Melkonian, Trevor R., Silvaggi, Nicholas R., Frick, David N.
Yayımlandı bioRxiv (2020)

Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3

Yazar: Virdi, Rajdeep S., Bavisotto, Robert V., Hopper, Nicholas C., Vuksanovic, Nemanja, Melkonian, Trevor R., Silvaggi, Nicholas R., Frick, David N.
Yayımlandı SLAS Discov (2020)

Ligand Binding Phenomena that Pertain to the Metabolic Function of Renalase

Yazar: Beaupre, Brett A., Roman, Joseph V., Hoag, Matthew R., Meneely, Kathleen M., Silvaggi, Nicholas R., Lamb, Audrey L., Moran, Graham R.
Yayımlandı Arch Biochem Biophys (2016)

A 1.2-Å snapshot of the final step of bacterial cell wall biosynthesis

Yazar: Lee, Wenlin, McDonough, Michael A., Kotra, Lakshmi P., Li, Zhi-Hong, Silvaggi, Nicholas R., Takeda, Yoshifumi, Kelly, Judith A., Mobashery, Shahriar
Baskı/Yayın Bilgisi 2001

The Aspartate-Less Receiver (ALR) Domains: Distribution, Structure and Function

Yazar: Maule, Andrew F., Wright, David P., Weiner, Joshua J., Han, Lanlan, Peterson, Francis C., Volkman, Brian F., Silvaggi, Nicholas R., Ulijasz, Andrew T.
Yayımlandı PLoS Pathog (2015)

Chirality Holds the Key for Potent Inhibition of the Botulinum Neurotoxin Serotype A Protease

Yazar: Stowe, G. Neil, Šilhár, Peter, Hixon, Mark S., Silvaggi, Nicholas R., Allen, Karen N., Moe, Scott T., Jacobson, Alan R., Barbieri, Joseph T., Janda, Kim D.
Baskı/Yayın Bilgisi 2010

Structural and Functional Characterization of MppR, an Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus: Functional Diversity in the Acetoacetate Decarboxylase-Li...

Yazar: Burroughs, A. Maxwell, Hoppe, Robert W., Goebel, Neal C., Sayyed, Bilal H., Voegtline, Tyler J., Schwabacher, Alan W., Zabriskie, T. Mark, Silvaggi, Nicholas R.
Baskı/Yayın Bilgisi 2013

Swit_4259, an acetoacetate decarboxylase-like enzyme from Sphingomonas wittichii RW1

Yazar: Mydy, Lisa S., Mashhadi, Zahra, Knight, T. William, Fenske, Tyler, Hagemann, Trevor, Hoppe, Robert W., Han, Lanlan, Miller, Todd R., Schwabacher, Alan W., Silvaggi, Nicholas R.
Yayımlandı Acta Crystallogr F Struct Biol Commun (2017)

Synthesis and Evaluation of Vitamin D Receptor-Mediated Activities of Cholesterol and Vitamin D Metabolites

Yazar: Teske, Kelly A., Bogart, Jonathan W., Sanchez, Luis M., Yu, Olivia B., Preston, Joshua V., Cook, James M., Silvaggi, Nicholas R., Bikle, Daniel D., Arnold, Leggy A.
Yayımlandı Eur J Med Chem (2016)

RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization

Yazar: Glanville, David G., Han, Lanlan, Maule, Andrew F., Woodacre, Alexandra, Thanki, Devsaagar, Abdullah, Iman Tajer, Morrissey, Julie A., Clarke, Thomas B., Yesilkaya, Hasan, Silvaggi, Nicholas R., Ulijasz, Andrew T.
Yayımlandı PLoS Pathog (2018)

IDENTIFICATION OF VDR ANTAGONISTS AMONG NUCLEAR RECEPTOR LIGANDS USING VIRTUAL SCREENING

Yazar: Teske, Kelly, Nandhikonda, Premchendar, Bogart, Jonathan W., Feleke, Belaynesh, Sidhu, Preetpal, Yuan, Nina, Preston, Joshua, Goy, Robin, Han, Lanlan, Silvaggi, Nicholas R, Singh, Rakesh K., Bikle, Daniel D., Cook, James M., Arnold, Leggy A.
Yayımlandı Nucl Receptor Res (2014)

Anticancer Activity of VDR-Coregulator Inhibitor PS121912

Yazar: Sidhu, Preetpal S., Teske, Kelly, Feleke, Belaynesh, Yuan, Nina Y., Guthrie, Margaret L., Fernstrum, Grant B., Vyas, Nishita D., Han, Lanlan, Preston, Joshua, Bogart, Jonathan W., Silvaggi, Nicholas R., Cook, James M., Singh, Rakesh K., Bikle, Daniel D., Arnold, Leggy A.
Baskı/Yayın Bilgisi 2014

Antitumor Activity of 3-Indolylmethanamines 31B and PS121912

Yazar: Guthrie, Margaret L, Sidhu, Preetpal S., Hill, Emily K., Horan, Timothy C., Nandhikonda, Premchendar, Teske, Kelly A., Yuan, Nina Y., Sidorko, Marina, Kodali, Revathi, Cook, James M., Han, Lanlan, Silvaggi, Nicholas R., Bikle, Daniel D., Moore, Richard G., Singh, Rakesh K., Arnold, Leggy A.
Yayımlandı Anticancer Res (2015)

Small Molecule Metalloprotease Inhibitor with in Vitro, Ex Vivo and In Vivo Efficacy Against Botulinum Neurotoxin Serotype A

Yazar: Jacobson, Alan R., Adler, Michael, Silvaggi, Nicholas R., Allen, Karen N., Smith, Genessa M., Fredenburg, Ross A., Stein, Ross L., Park, Jong-Beak, Mukherjee, Jean, Feng, Xiaochuan, Shoemaker, Charles B., Deshpande, Sharad S., Goodnough, Michael C., Malizio, Carl J., Johnson, Eric A., Pellett, Sabine, Tepp, William H., Tzipori, Saul
Yayımlandı Toxicon (2017)