RitR is an archetype for a novel family of redox sensors in the streptococci that has evolved from two-component response regulators and is required for pneumococcal colonization

To survive diverse host environments, the human pathogen Streptococcus pneumoniae must prevent its self-produced, extremely high levels of peroxide from reacting with intracellular iron. However, the regulatory mechanism(s) by which the pneumococcus accomplishes this balance remains largely enigmati...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Glanville, David G., Han, Lanlan, Maule, Andrew F., Woodacre, Alexandra, Thanki, Devsaagar, Abdullah, Iman Tajer, Morrissey, Julie A., Clarke, Thomas B., Yesilkaya, Hasan, Silvaggi, Nicholas R., Ulijasz, Andrew T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5965902/
https://ncbi.nlm.nih.gov/pubmed/29750817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007052
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