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Discovery of Drug-Like Ligands for the Mac1 Domain of SARS-CoV-2 Nsp3
Small molecules that bind the SARS-CoV-2 nonstructural protein 3 Mac1 domain in place of ADP-ribose could be useful as molecular probes or scaffolds for COVID-19 antiviral drug discovery because Mac1 has been linked to the ability of coronaviruses to evade cellular detection. A high-throughput assay...
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| Yayımlandı: | SLAS Discov |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Society for Laboratory Automation and Screening. Published by Elsevier Inc.
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7684785/ https://ncbi.nlm.nih.gov/pubmed/32981460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555220960428 |
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