Do all roads lead to Oct4? The emerging concepts of induced pluripotency

Por Radzisheuskaya, Aliaksandra, Silva, José C.R.
Publicado em 2014

Switching on pluripotency: a perspective on the biological requirement of Nanog

Por Theunissen, Thorold W., Silva, José C. R.
Publicado em 2011

JAK/STAT3 signalling is sufficient and dominant over antagonistic cues for the establishment of naive pluripotency

Por van oosten, Anouk L., Costa, Yael, Smith, Austin, Silva, José C.R.
Publicado em 2012

Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency

Por Yang, Jian, van Oosten, Anouk L., Theunissen, Thorold W., Guo, Ge, Silva, Jose C.R., Smith, Austin
Publicado em 2010

Nanog Overcomes Reprogramming Barriers and Induces Pluripotency in Minimal Conditions

Por Theunissen, Thorold W., van Oosten, Anouk L., Castelo-Branco, Gonçalo, Hall, John, Smith, Austin, Silva, José C.R.
Publicado em 2011

Exit from Naive Pluripotency Induces a Transient X Chromosome Inactivation-like State in Males

Por Sousa, Elsa J., Stuart, Hannah T., Bates, Lawrence E., Ghorbani, Mohammadmersad, Nichols, Jennifer, Dietmann, Sabine, Silva, José C.R.
Publicado no Cell Stem Cell (2018)

MBD3/NuRD Facilitates Induction of Pluripotency in a Context-Dependent Manner

Por dos Santos, Rodrigo L., Tosti, Luca, Radzisheuskaya, Aliaksandra, Caballero, Isabel M., Kaji, Keisuke, Hendrich, Brian, Silva, José C.R.
Publicado em 2014

MBD3/NuRD Facilitates Induction of Pluripotency in a Context-Dependent Manner

Por dos Santos, Rodrigo L., Tosti, Luca, Radzisheuskaya, Aliaksandra, Caballero, Isabel M., Kaji, Keisuke, Hendrich, Brian, Silva, José C.R.
Publicado no Cell Stem Cell (2014)

NANOG Amplifies STAT3 Activation and They Synergistically Induce the Naive Pluripotent Program

Por Stuart, Hannah T., van Oosten, Anouk L., Radzisheuskaya, Aliaksandra, Martello, Graziano, Miller, Anzy, Dietmann, Sabine, Nichols, Jennifer, Silva, José C.R.
Publicado em 2014

Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency

Por Pasque, Vincent, Radzisheuskaya, Aliaksandra, Gillich, Astrid, Halley-Stott, Richard P., Panamarova, Maryna, Zernicka-Goetz, Magdalena, Surani, M. Azim, Silva, José C. R.
Publicado em 2012

Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain

Por Theunissen, Thorold W., Costa, Yael, Radzisheuskaya, Aliaksandra, van Oosten, Anouk L., Lavial, Fabrice, Pain, Bertrand, Castro, L. Filipe C., Silva, José C. R.
Publicado em 2011

A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages

Por Radzisheuskaya, Aliaksandra, Chia, Gloryn Le Bin, dos Santos, Rodrigo L., Theunissen, Thorold W., Castro, L. Filipe C., Nichols, Jennifer, Silva, José C. R.
Publicado em 2013

Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming

Por Fidalgo, Miguel, Faiola, Francesco, Pereira, Carlos-Filipe, Ding, Junjun, Saunders, Arven, Gingold, Julian, Schaniel, Christoph, Lemischka, Ihor R., Silva, José C. R., Wang, Jianlong
Publicado em 2012

One-step generation of conditional and reversible gene knockouts

Por Andersson-Rolf, Amanda, Mustata, Roxana C., Merenda, Alessandra, Kim, Jihoon, Perera, Sajith, Grego, Tiago, Andrews, Katie, Tremble, Katie, Silva, José C.R., Fink, Juergen, Skarnes, William C., Koo, Bon-Kyoung
Publicado no Nat Methods (2017)

Nanog-dependent function of Tet1 and Tet2 in establishment of pluripotency

Por Costa, Yael, Ding, Junjun, Theunissen, Thorold W., Faiola, Francesco, Hore, Timothy A., Shliaha, Pavel V., Fidalgo, Miguel, Saunders, Arven, Lawrence, Moyra, Dietmann, Sabine, Das, Satyabrata, Levasseur, Dana N., Li, Zhe, Xu, Mingjiang, Reik, Wolf, Silva, José C.R., Wang, Jianlong
Publicado em 2013