Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain

Pluripotency is a developmental ground state that can be recreated by direct reprogramming. Establishment of pluripotency is crucially dependent on the homeodomain-containing transcription factor Nanog. Compared with other pluripotency-associated genes, however, Nanog shows relatively low sequence c...

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Main Authors: Theunissen, Thorold W., Costa, Yael, Radzisheuskaya, Aliaksandra, van Oosten, Anouk L., Lavial, Fabrice, Pain, Bertrand, Castro, L. Filipe C., Silva, José C. R.
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2011
Fag:
Development and Stem Cells
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201656/
https://ncbi.nlm.nih.gov/pubmed/22028025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.068775
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