Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming

The homeodomain transcription factor Nanog plays an important role in embryonic stem cell (ESC) self-renewal and is essential for acquiring ground-state pluripotency during reprogramming. Understanding how Nanog is transcriptionally regulated is important for further dissecting mechanisms of ESC plu...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fidalgo, Miguel, Faiola, Francesco, Pereira, Carlos-Filipe, Ding, Junjun, Saunders, Arven, Gingold, Julian, Schaniel, Christoph, Lemischka, Ihor R., Silva, José C. R., Wang, Jianlong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2012
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3479613/
https://ncbi.nlm.nih.gov/pubmed/22988117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208533109
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