Downregulation of signal transducer and activator of transcription 3 by sorafenib: A novel mechanism for hepatocellular carcinoma therapy

Por Hung, Man-Hsin, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado no World J Gastroenterol (2014)

Gambogic acid is an antagonist of anti-apoptotic Bcl-2-family proteins

Por Zhai, Dayong, Jin, Chaofang, Shiau, Chung-wai, Kitada, Shinichi, Satterthwait, Arnold C, Reed, John C.
Publicado em 2008

Alteration of SHP-1/p-STAT3 Signaling: A Potential Target for Anticancer Therapy

Por Huang, Tzu-Ting, Su, Jung-Chen, Liu, Chun-Yu, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado no Int J Mol Sci (2017)

CIP2A is a target of bortezomib in human triple negative breast cancer cells

Por Tseng, Ling-Ming, Liu, Chun-Yu, Chang, Kung-Chi, Chu, Pei-Yi, Shiau, Chung-Wai, Chen , Kuen-Feng
Publicado em 2012

Nilotinib Induces Autophagy in Hepatocellular Carcinoma through AMPK Activation

Por Yu, Hui-Chuan, Lin, Chen-Si, Tai, Wei-Tien, Liu, Chun-Yu, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado em 2013

Cancerous Inhibitor of Protein Phosphatase 2A Mediates Bortezomib-Induced Autophagy in Hepatocellular Carcinoma Independent of Proteasome

Por Yu, Hui-Chuan, Hou, Duen-Ren, Liu, Chun-Yu, Lin, Chen-Si, Shiau, Chung-Wai, Cheng, Ann-Lii, Chen, Kuen-Feng
Publicado em 2013

Cancerous inhibitor of protein phosphatase 2A determines bortezomib-induced apoptosis in leukemia cells

Por Liu, Chun-Yu, Shiau, Chung-Wai, Kuo, Hsin-Yu, Huang, Hsiang-Po, Chen, Ming-Huang, Tzeng, Cheng-Hwai, Chen, Kuen-Feng
Publicado em 2013

Chemical Biology Investigation of Cell Death Pathways Activated by Endoplasmic Reticulum Stress Reveals Cytoprotective Modulators of ASK1

Por Kim, InKi, Shu, Chih-Wen, Xu, Wenjie, Shiau, Chung-Wai, Grant, Daniel, Vasile, Stefan, Cosford, Nicholas D. P., Reed, John C.
Publicado em 2009

Urolithin A suppresses the proliferation of endometrial cancer cells by mediating estrogen receptor-α-dependent gene expression

Por Zhang, Wei, Chen, Jo-Hsin, Aguilera-Barrantes, Irene, Shiau, Chung-Wai, Sheng, Xiugui, Wang, Li-Shu, Stoner, Gary D., Huang, Yi-Wen
Publicado no Mol Nutr Food Res (2016)

Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells

Por Liu, Chun-Yu, Tseng, Ling-Ming, Su, Jung-Chen, Chang, Kung-Chi, Chu, Pei-Yi, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado em 2013

Pharmacological Targeting SHP-1-STAT3 Signaling Is a Promising Therapeutic Approach for the Treatment of Colorectal Cancer()()

Por Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Tai, Wei-Tien, Hung, Man-Hsin, Yang, Shung-Haur, Jiang, Jeng-Kai, Chen, Kuen-Feng
Publicado no Neoplasia (2015)

Erratum to: Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells

Por Liu, Chun-Yu, Tseng, Ling-Ming, Su, Jung-Chen, Chang, Kung-Chi, Chu, Pei-Yi, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado no Breast Cancer Res (2017)

Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer

Por Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Tai, Wei-Tien, Hung, Man-Hsin, Yang, Shung-Haur, Jiang, Jeng-Kai, Chen, Kuen-Feng
Publicado no Oncotarget (2016)

Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody

Por Chen, Kuen-Feng, Chen, Hui-Ling, Shiau, Chung-Wai, Liu, Chun-Yu, Chu, Pei-Yi, Tai, Wei-Tien, Ichikawa, Kimihisa, Chen, Pei-Jer, Cheng, Ann-Lii
Publicado em 2013

Targeting SHP-1-STAT3 signaling: A promising therapeutic approach for the treatment of cholangiocarcinoma

Por Hu, Ming-Hung, Chen, Li-Ju, Chen, Yen-Lin, Tsai, Ming-Shen, Shiau, Chung-Wai, Chao, Tzu-I, Liu, Chun-Yu, Kao, Jia-Horng, Chen, Kuen-Feng
Publicado no Oncotarget (2017)

Fragment-Based Design of Small Molecule X-Linked Inhibitor of Apoptosis Protein Inhibitors

Por Huang, Jui-Wen, Zhang, Ziming, Wu, Bainan, Cellitti, Jason F., Zhang, Xiyun, Dahl, Russell, Shiau, Chung-Wai, Welsh, Kate, Emdadi, Aras, Stebbins, John L., Reed, John C., Pellecchia, Maurizio
Publicado em 2008

SHP-1 is a target of regorafenib in colorectal cancer

Por Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Lin, Hang, Hung, Man-Hsin, Chen, Yen-Lin, Huang, Jui-Wen, Tai, Wei-Tien, Yu, Hui-Chuan, Chen, Kuen-Feng
Publicado em 2014

RFX1–dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells

Por Su, Jung-Chen, Tseng, Ping-Hui, Hsu, Cheng-Yi, Tai, Wei-Tien, Huang, Jui-Wen, Ko, Ching-Huai, Lin, Mai-Wei, Liu, Chun-Yu, Chen, Kuen-Feng, Shiau, Chung-Wai
Publicado em 2014

SC-2001 Overcomes STAT3-mediated Sorafenib Resistance through RFX-1/SHP-1 Activation in Hepatocellular Carcinoma()()

Por Su, Jung-Chen, Tseng, Ping-Hui, Wu, Szu-Hsien, Hsu, Cheng-Yi, Tai, Wei-Tien, Li, Yong-Shi, Chen, I-Ting, Liu, Chun-Yu, Chen, Kuen-Feng, Shiau, Chung-Wai
Publicado em 2014

SET antagonist enhances the chemosensitivity of non-small cell lung cancer cells by reactivating protein phosphatase 2A

Por Hung, Man-Hsin, Wang, Cheng-Yi, Chen, Yen-Lin, Chu, Pei-Yi, Hsiao, Yung-Jen, Tai, Wei-Tien, Chao, Ting-Ting, Yu, Hui-Chuan, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado no Oncotarget (2015)