Treatment of Liver Cancer

Por Liu, Chun-Yu, Chen, Kuen-Feng, Chen, Pei-Jer
Publicado no Cold Spring Harb Perspect Med (2015)

Downregulation of signal transducer and activator of transcription 3 by sorafenib: A novel mechanism for hepatocellular carcinoma therapy

Por Hung, Man-Hsin, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado no World J Gastroenterol (2014)

CIP2A is a target of bortezomib in human triple negative breast cancer cells

Por Tseng, Ling-Ming, Liu, Chun-Yu, Chang, Kung-Chi, Chu, Pei-Yi, Shiau, Chung-Wai, Chen , Kuen-Feng
Publicado em 2012

Nilotinib Induces Autophagy in Hepatocellular Carcinoma through AMPK Activation

Por Yu, Hui-Chuan, Lin, Chen-Si, Tai, Wei-Tien, Liu, Chun-Yu, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado em 2013

Degradation of Epidermal Growth Factor Receptor Mediates Dasatinib-Induced Apoptosis in Head and Neck Squamous Cell Carcinoma Cells

Por Lin, Yu-Chin, Wu, Meng-Hsuan, Wei, Tzu-Tang, Chuang, Shu-Hui, Chen, Kuen-Feng, Cheng, Ann-Lii, Chen, Ching-Chow
Publicado em 2012

Cancerous Inhibitor of Protein Phosphatase 2A Mediates Bortezomib-Induced Autophagy in Hepatocellular Carcinoma Independent of Proteasome

Por Yu, Hui-Chuan, Hou, Duen-Ren, Liu, Chun-Yu, Lin, Chen-Si, Shiau, Chung-Wai, Cheng, Ann-Lii, Chen, Kuen-Feng
Publicado em 2013

Cancerous inhibitor of protein phosphatase 2A determines bortezomib-induced apoptosis in leukemia cells

Por Liu, Chun-Yu, Shiau, Chung-Wai, Kuo, Hsin-Yu, Huang, Hsiang-Po, Chen, Ming-Huang, Tzeng, Cheng-Hwai, Chen, Kuen-Feng
Publicado em 2013

Bortezomib Overcomes Tumor Necrosis Factor-related Apoptosis-inducing Ligand Resistance in Hepatocellular Carcinoma Cells in Part through the Inhibition of the Phosphatidylinosit...

Por Chen, Kuen-Feng, Yeh, Pei-Yen, Hsu, Chiun, Hsu, Chih-Hung, Lu, Yen-Shen, Hsieh, Hsing-Pang, Chen, Pei-Jer, Cheng, Ann-Lii
Publicado em 2009

Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells

Por Liu, Chun-Yu, Tseng, Ling-Ming, Su, Jung-Chen, Chang, Kung-Chi, Chu, Pei-Yi, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado em 2013

Pharmacological Targeting SHP-1-STAT3 Signaling Is a Promising Therapeutic Approach for the Treatment of Colorectal Cancer()()

Por Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Tai, Wei-Tien, Hung, Man-Hsin, Yang, Shung-Haur, Jiang, Jeng-Kai, Chen, Kuen-Feng
Publicado no Neoplasia (2015)

Erratum to: Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells

Por Liu, Chun-Yu, Tseng, Ling-Ming, Su, Jung-Chen, Chang, Kung-Chi, Chu, Pei-Yi, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado no Breast Cancer Res (2017)

Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer

Por Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Tai, Wei-Tien, Hung, Man-Hsin, Yang, Shung-Haur, Jiang, Jeng-Kai, Chen, Kuen-Feng
Publicado no Oncotarget (2016)

Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody

Por Chen, Kuen-Feng, Chen, Hui-Ling, Shiau, Chung-Wai, Liu, Chun-Yu, Chu, Pei-Yi, Tai, Wei-Tien, Ichikawa, Kimihisa, Chen, Pei-Jer, Cheng, Ann-Lii
Publicado em 2013

SHP-1 is a target of regorafenib in colorectal cancer

Por Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Lin, Hang, Hung, Man-Hsin, Chen, Yen-Lin, Huang, Jui-Wen, Tai, Wei-Tien, Yu, Hui-Chuan, Chen, Kuen-Feng
Publicado em 2014

Synergistic interactions between imatinib mesylate and the novel phosphoinositide-dependent kinase-1 inhibitor OSU-03012 in overcoming imatinib mesylate resistance

Por Tseng, Ping-Hui, Lin, Ho-Pi, Zhu, Jiuxiang, Chen, Kuen-Feng, Hade, Erinn M., Young, Donn C., Byrd, John C., Grever, Michael, Johnson, Kara, Druker, Brian J., Chen, Ching-Shih
Publicado em 2005

RFX1–dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells

Por Su, Jung-Chen, Tseng, Ping-Hui, Hsu, Cheng-Yi, Tai, Wei-Tien, Huang, Jui-Wen, Ko, Ching-Huai, Lin, Mai-Wei, Liu, Chun-Yu, Chen, Kuen-Feng, Shiau, Chung-Wai
Publicado em 2014

SC-2001 Overcomes STAT3-mediated Sorafenib Resistance through RFX-1/SHP-1 Activation in Hepatocellular Carcinoma()()

Por Su, Jung-Chen, Tseng, Ping-Hui, Wu, Szu-Hsien, Hsu, Cheng-Yi, Tai, Wei-Tien, Li, Yong-Shi, Chen, I-Ting, Liu, Chun-Yu, Chen, Kuen-Feng, Shiau, Chung-Wai
Publicado em 2014

SET antagonist enhances the chemosensitivity of non-small cell lung cancer cells by reactivating protein phosphatase 2A

Por Hung, Man-Hsin, Wang, Cheng-Yi, Chen, Yen-Lin, Chu, Pei-Yi, Hsiao, Yung-Jen, Tai, Wei-Tien, Chao, Ting-Ting, Yu, Hui-Chuan, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado no Oncotarget (2015)

SH2 domain-containing phosphatase 1 regulates pyruvate kinase M2 in hepatocellular carcinoma

Por Tai, Wei-Tien, Hung, Man-Hsin, Chu, Pei-Yi, Chen, Yao-Li, Chen, Li-Ju, Tsai, Ming-Hsien, Chen, Min-Husan, Shiau, Chung-Wai, Boo, Yin-Pin, Chen, Kuen-Feng
Publicado no Oncotarget (2016)

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A

Por Chao, Ting-Ting, Wang, Cheng-Yi, Chen, Yen-Lin, Lai, Chih-Cheng, Chang, Fang-Yu, Tsai, Yi-Ting, Chao, Chung-Hao H., Shiau, Chung-Wai, Huang, Yuh-Chin T., Yu, Chong-Jen, Chen, Kuen-Feng
Publicado no Oncotarget (2014)