Downregulation of signal transducer and activator of transcription 3 by sorafenib: A novel mechanism for hepatocellular carcinoma therapy

Por Hung, Man-Hsin, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado no World J Gastroenterol (2014)

Comment on “ALK is a therapeutic target for lethal sepsis”

Por Blasco, Rafael B., Patrucco, Enrico, Mota, Ines, Tai, Wei-Tien, Chiarle, Roberto
Publicado no Sci Transl Med (2018)

Nilotinib Induces Autophagy in Hepatocellular Carcinoma through AMPK Activation

Por Yu, Hui-Chuan, Lin, Chen-Si, Tai, Wei-Tien, Liu, Chun-Yu, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado em 2013

Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells

Por Liu, Chun-Yu, Tseng, Ling-Ming, Su, Jung-Chen, Chang, Kung-Chi, Chu, Pei-Yi, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado em 2013

Pharmacological Targeting SHP-1-STAT3 Signaling Is a Promising Therapeutic Approach for the Treatment of Colorectal Cancer()()

Por Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Tai, Wei-Tien, Hung, Man-Hsin, Yang, Shung-Haur, Jiang, Jeng-Kai, Chen, Kuen-Feng
Publicado no Neoplasia (2015)

Erratum to: Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells

Por Liu, Chun-Yu, Tseng, Ling-Ming, Su, Jung-Chen, Chang, Kung-Chi, Chu, Pei-Yi, Tai, Wei-Tien, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado no Breast Cancer Res (2017)

Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer

Por Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Tai, Wei-Tien, Hung, Man-Hsin, Yang, Shung-Haur, Jiang, Jeng-Kai, Chen, Kuen-Feng
Publicado no Oncotarget (2016)

Sorafenib and its derivative SC-49 sensitize hepatocellular carcinoma cells to CS-1008, a humanized anti-TNFRSF10B (DR5) antibody

Por Chen, Kuen-Feng, Chen, Hui-Ling, Shiau, Chung-Wai, Liu, Chun-Yu, Chu, Pei-Yi, Tai, Wei-Tien, Ichikawa, Kimihisa, Chen, Pei-Jer, Cheng, Ann-Lii
Publicado em 2013

SHP-1 is a target of regorafenib in colorectal cancer

Por Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Lin, Hang, Hung, Man-Hsin, Chen, Yen-Lin, Huang, Jui-Wen, Tai, Wei-Tien, Yu, Hui-Chuan, Chen, Kuen-Feng
Publicado em 2014

RFX1–dependent activation of SHP-1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells

Por Su, Jung-Chen, Tseng, Ping-Hui, Hsu, Cheng-Yi, Tai, Wei-Tien, Huang, Jui-Wen, Ko, Ching-Huai, Lin, Mai-Wei, Liu, Chun-Yu, Chen, Kuen-Feng, Shiau, Chung-Wai
Publicado em 2014

SC-2001 Overcomes STAT3-mediated Sorafenib Resistance through RFX-1/SHP-1 Activation in Hepatocellular Carcinoma()()

Por Su, Jung-Chen, Tseng, Ping-Hui, Wu, Szu-Hsien, Hsu, Cheng-Yi, Tai, Wei-Tien, Li, Yong-Shi, Chen, I-Ting, Liu, Chun-Yu, Chen, Kuen-Feng, Shiau, Chung-Wai
Publicado em 2014

SET antagonist enhances the chemosensitivity of non-small cell lung cancer cells by reactivating protein phosphatase 2A

Por Hung, Man-Hsin, Wang, Cheng-Yi, Chen, Yen-Lin, Chu, Pei-Yi, Hsiao, Yung-Jen, Tai, Wei-Tien, Chao, Ting-Ting, Yu, Hui-Chuan, Shiau, Chung-Wai, Chen, Kuen-Feng
Publicado no Oncotarget (2015)

SH2 domain-containing phosphatase 1 regulates pyruvate kinase M2 in hepatocellular carcinoma

Por Tai, Wei-Tien, Hung, Man-Hsin, Chu, Pei-Yi, Chen, Yao-Li, Chen, Li-Ju, Tsai, Ming-Hsien, Chen, Min-Husan, Shiau, Chung-Wai, Boo, Yin-Pin, Chen, Kuen-Feng
Publicado no Oncotarget (2016)

Disrupting VEGF-A paracrine and autocrine loops by targeting SHP-1 suppresses triple negative breast cancer metastasis

Por Su, Jung-Chen, Mar, Ai-Chung, Wu, Szu-Hsien, Tai, Wei-Tien, Chu, Pei-Yi, Wu, Chia-Yun, Tseng, Ling-Ming, Lee, Te-Chang, Chen, Kuen-Feng, Liu, Chun-Yu, Chiu, Hao-Chieh, Shiau, Chung-Wai
Publicado no Sci Rep (2016)

Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition

Por Su, Tung-Hung, Shiau, Chung-Wai, Jao, Ping, Liu, Chen-Hua, Liu, Chun-Jen, Tai, Wei-Tien, Jeng, Yung-Ming, Yang, Hung-Chih, Tseng, Tai-Chung, Huang, Hsiang-Po, Cheng, Huei-Ru, Chen, Pei-Jer, Chen, Kuen-Feng, Kao, Jia-Horng, Chen, Ding-Shinn
Publicado no Proc Natl Acad Sci U S A (2015)

Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis

Por Su, Tung-Hung, Shiau, Chung-Wai, Jao, Ping, Yang, Nian-Jie, Tai, Wei-Tien, Liu, Chun-Jen, Tseng, Tai-Chung, Yang, Hung-Chih, Liu, Chen-Hua, Huang, Kai-Wen, Hu, Ting-Chen, Huang, Yu-Jen, Wu, Yao-Ming, Chen, Li-Ju, Chen, Pei-Jer, Chen, Ding-Shinn, Chen, Kuen-Feng, Kao, Jia-Horng
Publicado no Sci Rep (2017)