Disrupting VEGF-A paracrine and autocrine loops by targeting SHP-1 suppresses triple negative breast cancer metastasis

Patients with triple-negative breast cancer (TNBC) had an increased likelihood of distant recurrence and death, as compared with those with non-TNBC subtype. Regorafenib is a multi-receptor tyrosine kinase (RTK) inhibitor targeting oncogenesis and has been approved for metastatic colorectal cancer a...

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Vydáno v:Sci Rep
Hlavní autoři: Su, Jung-Chen, Mar, Ai-Chung, Wu, Szu-Hsien, Tai, Wei-Tien, Chu, Pei-Yi, Wu, Chia-Yun, Tseng, Ling-Ming, Lee, Te-Chang, Chen, Kuen-Feng, Liu, Chun-Yu, Chiu, Hao-Chieh, Shiau, Chung-Wai
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4929457/
https://ncbi.nlm.nih.gov/pubmed/27364975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28888
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