Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer

Epithelial-to-mesenchymal transition (EMT) is well-known to evoke cancer invasion/metastasis, leading to a high frequency of mortality in patients with metastatic colorectal cancer (mCRC). Protein tyrosine phosphatase (PTPase)-targeted therapy has been identified as a novel cancer therapeutic. Previ...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fan, Li-Ching, Teng, Hao-Wei, Shiau, Chung-Wai, Tai, Wei-Tien, Hung, Man-Hsin, Yang, Shung-Haur, Jiang, Jeng-Kai, Chen, Kuen-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325431/
https://ncbi.nlm.nih.gov/pubmed/27580057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11636
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