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Regorafenib reverses HGF‐induced sorafenib resistance by inhibiting epithelial‐mesenchymal transition in hepatocellular carcinoma

Sorafenib resistance is one of the major obstacles towards achieving a better outcome in patients with advanced hepatocellular carcinoma (HCC), in which aberrant activation of the hepatocyte growth factor (HGF)/mesenchymal‐epithelial transition pathway is frequently observed. Here, we report that HC...

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Bibliografiske detaljer
Udgivet i:FEBS Open Bio
Main Authors: Chen, Weibo, Yang, Junsheng, Zhang, Yue, Cai, Huihua, Chen, Xuemin, Sun, Donglin
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356182/
https://ncbi.nlm.nih.gov/pubmed/30761258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12578
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