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Regorafenib (Stivarga) pharmacologically targets epithelial-mesenchymal transition in colorectal cancer
Epithelial-to-mesenchymal transition (EMT) is well-known to evoke cancer invasion/metastasis, leading to a high frequency of mortality in patients with metastatic colorectal cancer (mCRC). Protein tyrosine phosphatase (PTPase)-targeted therapy has been identified as a novel cancer therapeutic. Previ...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5325431/ https://ncbi.nlm.nih.gov/pubmed/27580057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11636 |
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