Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma

Protein tyrosine phosphatase 1B (PTP1B) is known to promote the pathogenesis of diabetes and obesity by negatively regulating insulin and leptin pathways, but its role associated with colon carcinogenesis is still under debate. In this study, we demonstrated the oncogenic role of PTP1B in promoting...

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Publicado no:Sci Rep
Main Authors: Teng, Hao-Wei, Hung, Man-Hsin, Chen, Li-Ju, Chang, Mao-Ju, Hsieh, Feng-Shu, Tsai, Ming-Hsien, Huang, Jui-Wen, Lin, Chih-Lung, Tseng, Hsiang-Wen, Kuo, Zong-Keng, Jiang, Jeng-Kai, Yang, Shung-Haur, Shiau, Chung-Wai, Chen, Kuen-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082755/
https://ncbi.nlm.nih.gov/pubmed/27752061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35308
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