Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis

This study aimed to investigate the role of src-homology protein tyrosine phosphatase-1 (SHP-1)–signal transducer and activator of transcription 3 (STAT3) pathway in liver fibrogenesis and the anti-fibrotic effect of SHP-1 agonist. The antifibrotic activity of SC-43, a sorafenib derivative with an e...

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Publicado no:Sci Rep
Main Authors: Su, Tung-Hung, Shiau, Chung-Wai, Jao, Ping, Yang, Nian-Jie, Tai, Wei-Tien, Liu, Chun-Jen, Tseng, Tai-Chung, Yang, Hung-Chih, Liu, Chen-Hua, Huang, Kai-Wen, Hu, Ting-Chen, Huang, Yu-Jen, Wu, Yao-Ming, Chen, Li-Ju, Chen, Pei-Jer, Chen, Ding-Shinn, Chen, Kuen-Feng, Kao, Jia-Horng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431996/
https://ncbi.nlm.nih.gov/pubmed/28496142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01572-z
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