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Cancerous inhibitor of protein phosphatase 2A determines bortezomib-induced apoptosis in leukemia cells
The multiple cellular targets affected by proteasome inhibition implicate a potential role for bortezomib, a first-in-class proteasome inhibitor, in enhancing antitumor activities in hematologic malignancies. Here, we examined the antitumor activity and drug targets of bortezomib in leukemia cells....
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Ferrata Storti Foundation
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3640117/ https://ncbi.nlm.nih.gov/pubmed/22983581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.050187 |
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